Verma Shyam B, Vasani Resham
Consultant Dermatologist, Nirvana Skin Clinic, Vadodara, India.
Consultant Dermatologist, Anand Polyclinic, Mumbai, India.
Mycoses. 2016 Oct;59(10):606-14. doi: 10.1111/myc.12503. Epub 2016 Mar 30.
Genital dermatophytosis has been considered rare by most Western authorities. However, to the contrary, Indian reports have shown a higher prevalence of genital dermatophytosis due to warm and humid climate, overcrowding and lack of hygiene. A review is presented for 24 cases of male genital dermatophytosis occurring in patients suffering from tinea cruris in India who have been randomly applying various broad-spectrum steroid antifungal and antibacterial creams containing one or more antifungal and antibiotic in addition to potent corticosteroids, mainly clobetasol propionate. This is such a common phenomenon that Indian dermatologists are witnessing an epidemic of sorts of steroid-modified dermatophytosis and we hereby share various clinical presentations of dermatophytosis of penis and/or scrotum in patients with tinea cruris who have been applying the above-mentioned creams. The review also discusses the bleak scenario that prevails in India regarding the drug regulatory affairs that allow such dangerous and irrational combinations that are sold over the counter because of misinterpretation of the law and lax implementation of existing laws.
大多数西方权威机构认为生殖器皮肤癣菌病较为罕见。然而，恰恰相反，印度的报告显示，由于气候温暖潮湿、人口密集和卫生条件差，生殖器皮肤癣菌病的患病率较高。本文对印度24例患有股癣的男性生殖器皮肤癣菌病患者进行了综述，这些患者一直在随意涂抹各种广谱类固醇抗真菌和抗菌乳膏，这些乳膏除了含有强效皮质类固醇（主要是丙酸氯倍他索）外，还含有一种或多种抗真菌药和抗生素。这种现象非常普遍，以至于印度皮肤科医生正在目睹一种类固醇性皮肤癣菌病的流行，在此我们分享股癣患者在涂抹上述乳膏后阴茎和/或阴囊皮肤癣菌病的各种临床表现。该综述还讨论了印度药品监管事务中盛行的严峻情况，由于对法律的误解和现有法律执行不力，导致此类危险且不合理的药物组合在柜台出售。
