Ma L P, Xu P, Sun D Y, Li N, Yang W J, Zhang L, Bai Y J, Ju L H, He H J, Chen W Y, Lyu P
Division of Policy Research and Social Sciences, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2016 Apr;50(4):339-45. doi: 10.3760/cma.j.issn.0253-9624.2016.04.011.
To investigate the quality of life and its related factors among HIV/AIDS patients from HIV serodiscordant couples in Zhoukou city of Henan province.
During January to May in 2015, by the convenience sample, World Health Organization Quality of Life Questionnaire for Brief Version (WHOQOL-BREF) (Chinese version) and a self-edited questionnaire were used to investigate 1 251 HIV/AIDS patients who were confirmed with HIV positive by local CDC, registered in"HIV serodiscordant family" and agreed to participate in a face-to-face interview with above 18 year-old based on the local CDC , township hospitals and village clinics of 9 counties and 1 district of Zhoukou city, excluding the HIV/AIDS patients who were in divorce, death by one side, unknowing about his HIV status, with mental illness and disturbance of consciousness, incorrectly understanding the content of the questionnaire, and reluctant to participate in this study. The scores of quality of life of physical, psychological, social relations, and environmental domain were calculated. The related factors of the scores of different domains were analyzed by Multiple Two Classification Unconditioned Logistic Regression.
The scores of investigation objects in the physical, psychological, social relations, and environmental domain were 12.00± 2.02, 12.07 ± 2.07, 11.87 ± 1.99, and 11.09 ± 1.84, respectively. The multiple Unconditioned Logistic Regression analysis indicated that age <40 years, on ART and no other sickness in last two weeks were beneficial factors associated with physical domain with OR (95%CI): 0.61 (0.35-1.06), 0.52 (0.30-0.90), and 1.66 (1.09-2.52), respectively. The possibility of no poverty and no other sickness in last two weeks increased to 0.15(0.09-0.26) and 1.57(1.06-2.33) times of those who was in poverty and with other sickness in last two weeks in physical domain. The possibility of participants who were below 40 years old and with children increased to 0.58 (0.34-0.98) and 0.37 (0.23-0.57) times of who were above 40 years old and without children in psychological domain. The factors of with AIDS related symptoms, no children and with other sickness in last two week were found to be significantly associated with environmental domain with OR (95%CI): 0.65 (0.48-0.88), 0.66 (0.51-0.85), and 0.65 (0.51-0.84), respectively .
The scores of every domain of quality of life in HIV serodiscordant couples of Zhoukou city were good. Age, whether having AIDS related symptoms, whether to accept ART , children, status of poverty, and whether suffering from other diseases in last two weeks were the main factors associated with the quality of life.
调查河南省周口市HIV血清学不一致夫妻中HIV/AIDS患者的生活质量及其相关因素。
2015年1月至5月，采用方便抽样法，运用世界卫生组织生活质量简表（WHOQOL-BREF）（中文版）和自行编制的问卷，对在当地疾病预防控制中心确诊为HIV阳性、登记在“HIV血清学不一致家庭”且同意参与面对面访谈的1 251例18岁以上HIV/AIDS患者进行调查，调查地点为周口市9县1区的当地疾病预防控制中心、乡镇医院和村卫生室，排除离婚、一方死亡、不知自己HIV感染状况、患有精神疾病和意识障碍、对问卷内容理解错误以及不愿参与本研究的HIV/AIDS患者。计算生理、心理、社会关系和环境领域的生活质量得分。采用多因素二分类非条件Logistic回归分析不同领域得分的相关因素。
调查对象生理、心理、社会关系和环境领域的得分分别为12.00±2.02、12.07±2.07、11.87±1.99和11.09±1.84。多因素非条件Logistic回归分析显示，年龄<40岁、接受抗逆转录病毒治疗（ART）以及近两周无其他疾病是与生理领域相关的有利因素，其比值比（OR）（95%可信区间）分别为：0.61（0.35 - 1.06）、0.52（0.30 - 0.90）和1.66（1.09 - 2.52）。在生理领域，近两周无贫困和无其他疾病的可能性分别是近两周处于贫困和患有其他疾病者的0.15（0.09 - 0.26）倍和1.57（1.06 - 2.33）倍。在心理领域，40岁以下且有子女的参与者的可能性分别是40岁以上且无子女者的0.58（0.34 - 0.98）倍和0.37（0.23 - 0.57）倍。发现与艾滋病相关症状、无子女以及近两周患有其他疾病是与环境领域显著相关的因素，其OR（95%可信区间）分别为：0.65（0.48 - 0.88）、0.66（0.51 - 0.85）和0.65（0.51 - 0.84）。
周口市HIV血清学不一致夫妻生活质量各领域得分良好。年龄、是否有艾滋病相关症状、是否接受抗逆转录病毒治疗、子女情况、贫困状况以及近两周是否患有其他疾病是与生活质量相关的主要因素。
