Culvenor Adam G, Crossley Kay M
J Orthop Sports Phys Ther. 2016 Apr;46(4):232-4. doi: 10.2519/jospt.2016.0603.
Anterior cruciate ligament (ACL) rupture is a well-established risk factor for knee osteoarthritis (OA). Fifty to ninety percent of individuals will develop radiographic tibiofemoral OA within a decade after ACL injury and anterior cruciate ligament reconstruction (ACLR). Although less well recognized, radiographic patellofemoral OA is present in approximately 50% of individuals at more than 10 years after ACLR. This early-onset OA and its associated pain and functional limitations pose a particular challenge to younger adults with OA compared to an older OA population. Targeted interventions need to be developed to reduce the burden of early-onset OA following ACLR. Emerging evidence suggests that such interventions should target both the patellofemoral and tibiofemoral joints.
前交叉韧带(ACL)断裂是膝关节骨关节炎(OA)公认的危险因素。50%至90%的个体在ACL损伤和前交叉韧带重建(ACLR)后的十年内会发展为影像学上的胫股OA。虽然认识程度较低,但在ACLR后10年以上,约50%的个体存在影像学上的髌股OA。与老年OA人群相比,这种早发性OA及其相关的疼痛和功能限制给患有OA的年轻成年人带来了特殊挑战。需要制定有针对性的干预措施,以减轻ACLR后早发性OA的负担。新出现的证据表明,此类干预措施应针对髌股关节和胫股关节。