Hopkins James C A, Blazeby Jane M, Rogers Chris A, Welbourn Richard
Department of Upper Gastrointestinal Surgery and Bariatric Surgery, Musgrove Park Hospital, Taunton TA1 5DA, UK.
Centre for Surgical Research, School of Social and Community Medicine, University of Bristol, Bristol, UK.
Br Med Bull. 2016 Jun;118(1):64-72. doi: 10.1093/bmb/ldw012. Epub 2016 Mar 31.
Obesity levels in the UK have reached a sustained high and ∼4% of the population would be candidates for bariatric surgery based upon current UK NICE guidelines, which has important implications for Clinical Commissioning Groups.
Summary data from Cochrane systematic reviews, randomized controlled trials (RCTs) and cohort studies.
Currently, the only treatment that offers significant and durable weight loss for those with severe and complex obesity is surgery. Three operations account for 95% of all bariatric surgery in the UK, but the NHS offers surgery to only a small fraction of those who could benefit. Laparoscopic adjustable gastric banding (gastric banding) has potentially the lowest risk and up-front costs of the three procedures.
Reliable Level 1 evidence of the relative effectiveness of the operations is lacking.
As a point intervention, weight loss surgery together with the chronic disease management strategy for obesity can prevent significant future disease and mortality, and the NHS should embrace both.
Better RCT evidence is needed including clinical effectiveness and economic analysis to answer the important question 'which is the best of the three operations most frequently performed?' This review considers the current evidence for gastric banding for the treatment of severe and complex obesity.
英国的肥胖水平持续处于高位,根据英国国家卫生与临床优化研究所(NICE)目前的指南,约4%的人口符合减肥手术的标准,这对临床委托小组具有重要意义。
Cochrane系统评价、随机对照试验(RCT)和队列研究的汇总数据。
目前,对于重度和复杂性肥胖患者而言,唯一能实现显著且持久减重的治疗方法是手术。在英国,95%的减肥手术由三种手术构成,但英国国民医疗服务体系(NHS)只为一小部分可能受益的人提供手术。腹腔镜可调节胃束带术(胃束带术)在这三种手术中风险可能最低,前期成本也最低。
缺乏关于这些手术相对有效性的可靠一级证据。
作为一种针对性干预措施,减肥手术与肥胖慢性病管理策略相结合可以预防未来的重大疾病和死亡,NHS应该同时采用这两种方法。
需要更好的随机对照试验证据,包括临床有效性和经济分析,以回答“三种最常实施的手术中哪种最佳?”这个重要问题。本综述考虑了目前胃束带术治疗重度和复杂性肥胖的证据。