Zwaan Eva M, IJsselmuiden Alexander J J, van Rosmalen Joost, van Geuns Robert-Jan M, Amoroso Giovanni, Moerman Esther, Ritt Marco J P F, Schreuders Ton A R, Kofflard Marcel J M, Holtzer Carlo A J
Department of Cardiology, Albert Schweitzer Hospital, Dordrecht, The Netherlands.
Department of Biostatistics, Erasmus Medical Centre, Rotterdam, The Netherlands.
Catheter Cardiovasc Interv. 2016 Dec;88(7):1036-1043. doi: 10.1002/ccd.26525. Epub 2016 Apr 1.
The aim of this study is to provide a complete insight in the access-site morbidity and upper extremity function after Transradial Percutaneous Coronary Intervention (TR-PCI).
In percutaneous coronary intervention the Transradial Approach (TRA) is gaining popularity as a default technique. It is a very promising technique with respect to post-procedure complications, but the exact effects of TRA on upper extremity function are unknown.
The effects of trAnsRadial perCUtaneouS coronary intervention on upper extremity function (ARCUS) trial is a multicenter prospective cohort study that will be conducted in all patients admitted for TR-PCI. Clinical outcomes will be monitored during a follow-up of 6 months, with its primary endpoint at two weeks of follow-up. To investigate the complete upper extremity function, a combination of physical examinations and validated questionnaires will be used to provide information on anatomical integrity, strength, range of motion (ROM), coordination, sensibility, pain, and functioning in everyday life. Procedural and material specifications will be registered in order to include all possible aspects influencing upper extremity function.
Results from this study will elucidate the effect of TR-PCI on upper extremity function. This creates the opportunity to further optimize TR-PCI, to make improvements in functional outcome and to prevent morbidity regarding full upper extremity function. © 2016 Wiley Periodicals, Inc.
本研究旨在全面了解经桡动脉冠状动脉介入治疗（TR-PCI）后穿刺部位的发病率及上肢功能。
在冠状动脉介入治疗中，经桡动脉途径（TRA）作为一种常规技术正越来越受欢迎。就术后并发症而言，这是一项非常有前景的技术，但TRA对上肢功能的确切影响尚不清楚。
经桡动脉冠状动脉介入治疗对上肢功能的影响（ARCUS）试验是一项多中心前瞻性队列研究，将纳入所有接受TR-PCI的患者。在6个月的随访期间监测临床结局，主要终点为随访两周时的情况。为了全面评估上肢功能，将结合体格检查和经过验证的问卷，以提供有关解剖结构完整性、力量、活动范围（ROM）、协调性、感觉、疼痛及日常生活功能等方面的信息。将记录手术及材料规格，以便纳入所有可能影响上肢功能的因素。
本研究结果将阐明TR-PCI对上肢功能的影响。这为进一步优化TR-PCI、改善功能结局以及预防上肢整体功能相关的发病情况创造了机会。© 2016威利期刊公司。
