Gosden R G, Brown N, Grant K
Department of Physiology, University Medical School, Edinburgh, UK.
J Reprod Fertil. 1989 Mar;85(2):519-26. doi: 10.1530/jrf.0.0850519.
In a histological survey of 19 mammalian species, Call-Exner bodies of conventional size and appearance were found in only 5, namely, human, rhesus monkey, rabbit, guinea-pig and sheep. Rabbit ovaries were used for characterizing these bodies using quantitative histochemistry, lectin binding and electron microscopy. Call-Exner bodies were topographically distinct lacunae of the extracellular space probably containing hyaluronic acid with proteoglycan complexes. The staining characteristics of the antrum and Call-Exner bodies were generally similar. However, in contrast to the antrum, the smaller lacunae contained suspended filaments with a distinctive peripheral membrane upon which a rosette of granulosa cells was resting. The membrane and narrow intercellular clefts probably prevent much exchange of large glycosaminoglycan complexes with the antrum. The origin and significance of Call-Exner bodies require further study, but it is clear that they are associated with secretion rather than with necrosis as sometimes suggested.
在一项对19种哺乳动物的组织学调查中，仅在5种动物中发现了具有常规大小和外观的Call-Exner小体，即人类、恒河猴、兔子、豚鼠和绵羊。使用定量组织化学、凝集素结合和电子显微镜对兔卵巢进行研究以表征这些小体。Call-Exner小体是细胞外空间中地形上不同的腔隙，可能含有与蛋白聚糖复合物结合的透明质酸。卵泡腔和Call-Exner小体的染色特征通常相似。然而，与卵泡腔不同的是，较小的腔隙中含有悬浮的细丝，其具有独特的外周膜，一群颗粒细胞附着在该外周膜上。该膜和狭窄的细胞间裂隙可能会阻止大的糖胺聚糖复合物与卵泡腔进行大量交换。Call-Exner小体的起源和意义需要进一步研究，但很明显它们与分泌有关，而不是像有时所认为的那样与坏死有关。
