Ishikura A, Ikeda M, Kogure Y, Enkaku H, Watanabe K
Dept. of Neurosurgery, Kanazawa National Hospital.
Gan No Rinsho. 1989 Jan;35(2):293-7.
Discussed is an 8-year-old girl with a history of convulsive seizures. A sharply demarcated tumor, measuring 3 X 4 cm, was located in the right frontal lobe. The mass grey and cystic in the center, and microscopic specimen demonstrated bizarre, irregular, giant cell with a long vesicular nuclei and spindle-shaped cell. A perivascular pseudo-rosette formation also was seen, and silver impregnation revealed reticulin network and extracellular collagen fibers. The pathological entity of an intracranial giant celled glioblastoma remains controversial. This entity is considered a giant celled glioblastoma by some and a monstrocellular sarcoma by others. In this that the authors experienced, a CT scan showed a ring that formed a high density area and low density in the center at the right frontal lobe. Also reviewed and discussed are the historical aspects of a giant celled glioblastoma and radiologic problems that have been encountered.
讨论的是一名有惊厥性癫痫病史的8岁女孩。在右额叶发现一个边界清晰的肿瘤，大小为3×4厘米。肿块中央呈灰色且为囊性，显微镜下标本显示有奇异、不规则的巨细胞，核呈长泡状，还有梭形细胞。还可见血管周围假菊形团形成，银浸染显示有网状纤维网络和细胞外胶原纤维。颅内巨细胞胶质母细胞瘤的病理实体仍存在争议。一些人认为该实体是巨细胞胶质母细胞瘤，另一些人则认为是巨细胞肉瘤。在作者所经历的这个病例中，CT扫描显示右额叶有一个环形区域，中央为低密度，周边为高密度。同时还回顾和讨论了巨细胞胶质母细胞瘤的历史背景以及所遇到的放射学问题。
