Nitta T, Nakajima K, Shimoji T, Maeda M, Ishii S
No To Shinkei. 1986 Mar;38(3):259-63.
The pathological entity of intracranial giant cell tumor remains controversial, which has been considered a glioma (giant cell glioblastoma) by some and a sarcoma (monstrocellular sarcoma) by others. The authors present a case in which CT scan shows a wedge-shaped high density area at the left parietal lobe. This tumor expands explosively only a month on serial CT scan. The microscopic speciemen demonstrates the bizarre irregular giant cells with large vesicular nuclei, and glial proliferation and abundant reticulin fibers. Then we reviewed and discussed with emphasis on the historical aspect of giant cell tumor and also radiologic, therapeutic problem.
颅内巨细胞瘤的病理实体仍存在争议,一些人认为它是一种胶质瘤(巨细胞胶质母细胞瘤),而另一些人则认为它是一种肉瘤(巨细胞肉瘤)。作者报告了一例病例,CT扫描显示左侧顶叶有一个楔形高密度区。在连续CT扫描中,该肿瘤仅在一个月内就呈爆发性生长。显微镜下标本显示有奇异的不规则巨细胞,核大呈空泡状,伴有胶质细胞增生和丰富的网状纤维。然后我们进行了回顾和讨论,重点是巨细胞瘤的历史方面以及放射学和治疗问题。