Ninomiya J, Shoji T, Yamate N, Matsushima S, Kodama Y, Shioda A
Division of Thoracic Surgery, Nippon Medical School, Tokyo, Japan.
Nihon Geka Gakkai Zasshi. 1989 Jan;90(1):114-9.
For evaluating whether 2 types of expanded polytetrafluoroethylene, ringed E-PTFE graft can be utilized for venous reconstruction, especially, for superior vena caval reconstruction or not, the ringed E-PTFE grafts which had 10-15 micron fibril length and 30 micron fibril length were implanted between the innominate vein and the right atrium of the 20 dogs. The grafts were removed for histological and scanning electromicroscopic evaluation at intervals varying from one to twelve postoperative months. Overall patency rate was 62% and severe stenosis at the site of anastomosis was seen in 2 grafts. More than half of the graft showed mild to moderate intimal hyperplasia at the anastomotic sites and the early stage of thrombosis at the middle of the grafts. Mesenchymal cell infiltration was occurred in 46% of the grafts.
为评估两种类型的膨体聚四氟乙烯（E-PTFE）环形移植物是否可用于静脉重建，特别是上腔静脉重建，将原纤维长度为10 - 15微米和30微米的E-PTFE环形移植物植入20只犬的无名静脉与右心房之间。在术后1至12个月的不同时间间隔取出移植物进行组织学和扫描电镜评估。总体通畅率为62%，2个移植物在吻合部位出现严重狭窄。超过一半的移植物在吻合部位显示轻度至中度内膜增生，移植物中部出现早期血栓形成。46%的移植物发生间充质细胞浸润。
