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用于筛查妊娠期糖尿病的反射仪的精度

Precision of reflectance meters in screening for gestational diabetes.

作者信息

Carr S, Coustan D R, Martelly P, Brosco F, Rotondo L

机构信息

Women and Infants' Hospital, Brown University Program in Biology and Medicine, Providence, Rhode Island.

出版信息

Obstet Gynecol. 1989 May;73(5 Pt 1):727-31.

PMID:2704498
Abstract

The use of reflectance meters to screen for gestational diabetes has been advocated because of convenience and apparent accuracy. The present study addresses the possibility that imprecision of reflectance meters may affect the reliability of the blood sugar values obtained with their use. We tested four reflectance meters (Glucometer, Glucometer II, Glucoscan 3000, and Accuchek II) on 84 gravidas undergoing 1-hour, 50-g glucose screening, and calculated average coefficients of variation (9.6 +/- 10.9, 8.2 +/- 4.7, 6.8 +/- 4.5, and 7.4 +/- 4.4%, respectively). One-way analysis of variance testing indicated no significant difference between these values (P = .11). However, comparison with the coefficients of variation from standard laboratory technology (YSI Model 23A Glucose Analyzer) applied to simultaneously obtained venous samples (2.3 +/- 1.5, 1.5 +/- 0.6, 1.9 +/- 1.0, and 1.0 +/- 0.5%) revealed that the meters all had coefficients of variation significantly higher (P less than .0001). Use of reflectance meters would have resulted in 45.2% (38 of 84) of the subjects undergoing 3-hour oral glucose tolerance tests. Use of standard laboratory values would have indicated these tests in only 16% (14 of 84). The inconvenience and increased cost of these oral glucose tolerance tests suggest that meters may not be appropriate for screening.

摘要

由于操作便捷且准确性明显,反射仪被提倡用于筛查妊娠期糖尿病。本研究探讨了反射仪的不精确性可能影响其测得血糖值可靠性的可能性。我们对84名接受1小时50克葡萄糖筛查的孕妇使用了四种反射仪(血糖仪、血糖仪II、葡萄糖扫描3000和安妥血糖仪II),并计算了平均变异系数(分别为9.6±10.9%、8.2±4.7%、6.8±4.5%和7.4±4.4%)。单向方差分析表明这些值之间无显著差异(P = 0.11)。然而,将这些值与应用于同时采集的静脉血样本的标准实验室技术(YSI 23A葡萄糖分析仪)的变异系数(2.3±1.5%、1.5±0.6%、1.9±1.0%和1.0±0.5%)进行比较发现,所有反射仪的变异系数均显著更高(P小于0.0001)。使用反射仪会导致84名受试者中有45.2%(38名)接受3小时口服葡萄糖耐量试验。而使用标准实验室值仅表明16%(14名)的受试者需要进行这些试验。这些口服葡萄糖耐量试验带来的不便和成本增加表明反射仪可能不适用于筛查。

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