糖尿病患者Descemet膜和角膜内皮的形态学评估

Morphologic evaluation of Descemet's membrane and corneal endothelium in diabetes mellitus.

作者信息

Shetlar D J, Bourne W M, Campbell R J

机构信息

Department of Ophthalmology, Mayo Clinic and Foundation, Rochester, MN 55905.

出版信息

Ophthalmology. 1989 Feb;96(2):247-50. doi: 10.1016/s0161-6420(89)32908-3.

DOI:10.1016/s0161-6420(89)32908-3

PMID:2704544

Abstract

Diabetes mellitus is characterized by abnormally thickened basement membranes throughout the body and the eye. In addition, abnormal corneal endothelial cell morphology has been found in eyes of diabetics. The authors examined Descemet's membrane (the basement of the corneal endothelium) and the endothelial cells in 19 diabetic corneas and 19 age-matched nondiabetic normal corneas in a masked fashion by transmission electron microscopy and specular microscopy. No statistically significant quantitative or qualitative differences were found between the two groups.

摘要

糖尿病的特征是全身和眼部的基底膜异常增厚。此外，在糖尿病患者的眼睛中发现了异常的角膜内皮细胞形态。作者通过透射电子显微镜和镜面显微镜，以盲法检查了19只糖尿病角膜和19只年龄匹配的非糖尿病正常角膜的Descemet膜（角膜内皮的基底膜）和内皮细胞。两组之间未发现统计学上显著的定量或定性差异。