Bektas Sabaheta, Obradovic Amina, Aljicevic Mufida, Numanovic Fatima, Hodzic Dunja, Sporisevic Lutvo
Department of Microbiology, Institute for Public Health of Canton Sarajevo, Sarajevo, Bosnia and Herzegovina.
Faculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Mater Sociomed. 2016 Feb;28(1):61-5. doi: 10.5455/msm.2016.28.61-65. Epub 2016 Jan 30.
The increase in the incidence of methicillin-resistant Staphylococcus aureus (MRSA) infections lacking risk factors for exposure to the health care system has been associated with the recognition of new MRSA clones known as community-associated MRSA (CA-MRSA). These strains have been distinguished from health care-associated MRSA (HA-MRSA) strains by epidemiological, molecular and genetic means as well as by antibiotic susceptibility profile, tissue tropism and virulence traits.
To assess prevalence and antibiotic susceptibility profile of CA-MRSA in Canton Sarajevo, Bosnia and Herzegovina.
Out of 1.905 positive Staphylococcus aureus isolates from various samples of outpatients collected during six months, 279 (14,64%) were MRSA isolates. Out of 279 MRSA samples, 133 (47,67%) were found in nasal swabs, from which 48 (36,09%) were in the age group <1 year and 39 (29,32 %) are in the age 1-5 year. Rate of the positive skin swabs was highest among the subject of age group <1 year (46 or 54,12 %) and 1-5 year (18 or 21,18 %). Predominantly antibiotic types among MRSA strains are resistant to penicillin and cefoxitin (36,90 %) and to penicillin, cefoxitin and erythromycin (61,35 %).
Continued monitoring of epidemiology and emerging drug resistance data is critical for the effective management of these infections.
在缺乏医疗系统暴露风险因素的情况下,耐甲氧西林金黄色葡萄球菌(MRSA)感染发病率的增加与被称为社区相关性MRSA(CA-MRSA)的新MRSA克隆的出现有关。这些菌株已通过流行病学、分子和遗传学方法以及抗生素敏感性谱、组织嗜性和毒力特征与医疗保健相关性MRSA(HA-MRSA)菌株区分开来。
评估波斯尼亚和黑塞哥维那萨拉热窝州CA-MRSA的流行情况和抗生素敏感性谱。
在六个月期间收集的来自门诊患者各种样本的1905株金黄色葡萄球菌阳性分离株中,279株(14.64%)为MRSA分离株。在279份MRSA样本中,133份(47.67%)在鼻拭子中发现,其中48份(36.09%)在<1岁年龄组,39份(29.32%)在1-5岁年龄组。皮肤拭子阳性率在<1岁年龄组(46份或54.12%)和1-5岁年龄组(18份或21.18%)的受试者中最高。MRSA菌株中主要的抗生素类型对青霉素和头孢西丁耐药(36.90%),对青霉素、头孢西丁和红霉素耐药(61.35%)。
持续监测流行病学和新出现的耐药数据对于有效管理这些感染至关重要。