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退伍军人健康管理局新使用阿片类药物者的1年治疗疗程

The 1-Year Treatment Course of New Opioid Recipients in Veterans Health Administration.

作者信息

Mosher Hilary J, Richardson Kelly K, Lund Brian C

机构信息

*Center for Comprehensive Access and Delivery Research and Evaluation (CADRE) at the Iowa City VA Health Care System, Iowa City, Iowa.

The Department of Internal Medicine, University of Iowa, Carver College of Medicine, Iowa City, Iowa.

出版信息

Pain Med. 2016 Jul 1;17(7):1282-1291. doi: 10.1093/pm/pnw058.

Abstract

BACKGROUND

Understanding opioid prescribing trends requires differentiating clinically distinct short- and long-term receipt patterns.

OBJECTIVES

Describe the one-year course of opioid receipt among new opioid recipients and determine the proportion with subsequent long-term opioid therapy. Discern variation in proportion with long-term therapy initiation by geographic region and across Veterans Health Administration (VHA) medical centers.

METHODS

Longitudinal course of opioid receipt was analyzed using a cabinet supply approach. Short-term receipt was defined as index treatment episode lasting no longer than 30 days; long-term therapy as treatment episode of >90 days that began within the first 30 days following opioid index date.

PATIENTS

All VHA pharmacy users in 2004 and to 2011 who received a new prescription for an opioid (incident opioid recipients) preceded by 365 days with no opioid prescribed.

RESULTS

The proportion of all incident recipients who met the definition for long-term therapy within the first year decreased from 20.4% (N = 76,280) in 2004 to 18.3% (N = 96,166) in 2011. The proportion of incident recipients with chronic pain was unchanged between 2004 and 2011. Hydrocodone and tramadol increased as a proportion of initial opioids prescribed. Median days initially supplied decreased from 30 to 20 days. A greater percentage of new opioid prescriptions were for 7 days or fewer (20.9% in 2004; 27.9% in 2011). The proportion of new recipients who initiated long-term opioid therapy varied widely by medical center. Medical centers with higher proportions of new long-term recipients in 2004 saw greater decreases in this metric by 2011.

CONCLUSION

The proportion of new opioid recipients who initiated long-term opioid therapy declined between 2004 and 2011.

摘要

背景

了解阿片类药物的处方趋势需要区分临床上不同的短期和长期用药模式。

目的

描述新使用阿片类药物者一年的用药过程,并确定后续接受长期阿片类药物治疗的比例。辨别不同地理区域以及退伍军人健康管理局(VHA)各医疗中心长期治疗起始比例的差异。

方法

采用药品供应记录法分析阿片类药物的用药纵向过程。短期用药定义为索引治疗期不超过30天;长期治疗为在阿片类药物索引日期后的前30天内开始的持续超过90天的治疗期。

患者

2004年至2011年期间所有VHA药房使用者,这些人在接受阿片类药物新处方(新使用阿片类药物者)之前365天未开具过阿片类药物。

结果

在第一年符合长期治疗定义的所有新使用者比例从2004年的20.4%(N = 76,280)降至2011年的18.3%(N = 96,166)。2004年至2011年期间,患有慢性疼痛的新使用者比例没有变化。氢可酮和曲马多在初始开具的阿片类药物中所占比例增加。最初供应的中位数天数从30天降至20天。更高比例的阿片类药物新处方为7天或更短疗程(2004年为20.9%;2011年为27.9%)。开始长期阿片类药物治疗的新使用者比例在各医疗中心差异很大。2004年新长期使用者比例较高的医疗中心,到2011年这一指标下降幅度更大。

结论

2004年至2011年期间,开始长期阿片类药物治疗的新使用者比例有所下降。

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