Hadlandsmyth Katherine, Mosher Hilary J, Bayman Emine O, Wikle Justin G, Lund Brian C
Center for Access and Delivery Research and Evaluation (CADRE), Iowa City VA Healthcare System, Iowa City, IA, USA.
Department of Anesthesia, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
J Gen Intern Med. 2020 Sep;35(9):2607-2613. doi: 10.1007/s11606-020-05749-7. Epub 2020 Mar 23.
Narrow definitions of long-term opioid (LTO) use result in limited knowledge of the full range of LTO prescribing patterns and the rates of these patterns.
To investigate a model of new LTO prescribing typologies using latent class analysis.
National administrative data from the VA Corporate Data Warehouse were accessed using the VA Informatics and Computing Infrastructure. Characterization of the typology of initial LTO prescribing was explored using latent class analysis.
Veterans initiating LTO during 2016 through the Veteran's Administration Healthcare System (N = 42,230).
Opioid receipt as determined by VA prescription data, using the cabinet supply methodology.
Over one-quarter (27.7%) of the sample fell into the fragmented new long-term prescribing category, 39.8% were characterized by uniform daily new LTO, and the remaining 32.7% were characterized by uniform episodic LTO. Each of these three broad sub-groups also included two additional sub-groups (6 classes total in the model), characterized by the presence or absence of prior opioid prescriptions.
New LTO prescribing in the VA includes uniform daily prescribing, uniform episodic prescribing, and fragmented prescribing. Future work is needed to elucidate the safety and efficacy of these prescribing patterns.
对长期使用阿片类药物(LTO)的狭义定义导致对LTO处方模式的全貌及其发生率的了解有限。
使用潜在类别分析研究新的LTO处方类型模型。
通过退伍军人事务部信息学和计算基础设施访问来自退伍军人事务部企业数据仓库的国家行政数据。使用潜在类别分析探索初始LTO处方类型的特征。
2016年通过退伍军人事务部医疗保健系统开始使用LTO的退伍军人(N = 42,230)。
使用药柜供应方法,根据退伍军人事务部处方数据确定阿片类药物的使用情况。
超过四分之一(27.7%)的样本属于零散的新长期处方类别,39.8%的特征是每日统一的新LTO,其余32.7%的特征是间歇性统一LTO。这三个广泛的亚组中的每一个还包括另外两个亚组(模型中总共6类),其特征是有无先前的阿片类药物处方。
退伍军人事务部的新LTO处方包括每日统一处方、间歇性统一处方和零散处方。需要进一步的研究来阐明这些处方模式的安全性和有效性。