Islam A, Muir-Hunter S W, Speechley M, Montero-Odasso M
Manuel Montero-Odasso, Gait and Brain Lab, Parkwood Hospital, Room A-283, 801 Commissioners Road East, London, Ontario, CANADA, N6C 5J1, Phone: (519) 685-4292 ext. 42369, Fax: (519) 685-4093, Email:
J Frailty Aging. 2014;3(4):216-21. doi: 10.14283/jfa.2014.27.
Frailty is characterized by increased vulnerability for adverse events such as falls, fractures, placement, and death. Several frailty models have been developed, including the widely accepted Frailty Phenotype. However, the Frailty Phenotype can be difficult to apply in clinical practice. Alternatively, the Clinical Frailty Scale has been proposed based on its simplicity. To date, the Clinical Frailty Scale has not been validated against the Frailty Phenotype.
We aimed to test the inter-rater reliability of the Clinical Frailty Scale and its agreement with the Frailty Phenotype in frailty identification.
Cross-sectional study.
Retirement community in London, Ontario, Canada.
One hundred and four community-dwelling older adults (age ≥75 years).
Participants were first classified using the Frailty Phenotype criteria as not frail, pre-frail or frail. Subsequently, two clinicians blinded to the first assessment, determined frailty status using the Clinical Frailty Scale. Differences between assessments were resolved by consensus. Inter-rater reliability was assessed using kappa statistics. Spearman Rho correlation coefficients evaluated the concurrent validity of the Clinical Frailty Scale against Frailty Phenotype components.
Analysis with kappa statistic showed substantial agreement between raters in applying the Clinical Frailty Scale to the sample (κw= 0.76, 95% CI 0.68, 0.84). The Clinical Frailty Scale scores also positively correlated with an increasing number of Frailty Phenotype components (ρ=0.69, p<0.01).
The Clinical Frailty Scale is reliable and comparable to the Frailty Phenotype in identifying frailty in community-dwelling older adults with the advantage of being easy to administer in clinical settings. Reliable tools to identify frailty in community-dwelling older adults may help provide timely interventions to ameliorate risk of adverse events.
衰弱的特征是发生跌倒、骨折、入住机构及死亡等不良事件的易感性增加。已经开发了多种衰弱模型,包括广泛认可的衰弱表型。然而,衰弱表型在临床实践中可能难以应用。另外,基于其简单性,有人提出了临床衰弱量表。迄今为止,临床衰弱量表尚未与衰弱表型进行验证。
我们旨在测试临床衰弱量表的评分者间信度及其在衰弱识别中与衰弱表型的一致性。
横断面研究。
加拿大安大略省伦敦市的退休社区。
104名社区居住的老年人(年龄≥75岁)。
参与者首先根据衰弱表型标准分为非衰弱、衰弱前期或衰弱。随后,两名对首次评估不知情的临床医生使用临床衰弱量表确定衰弱状态。评估之间的差异通过共识解决。使用kappa统计量评估评分者间信度。Spearman Rho相关系数评估临床衰弱量表相对于衰弱表型各组成部分的同时效度。
kappa统计分析显示,评分者在对样本应用临床衰弱量表方面具有高度一致性(κw = 0.76,95% CI 0.68,0.84)。临床衰弱量表得分也与衰弱表型组成部分数量的增加呈正相关(ρ = 0.69,p < 0.01)。
临床衰弱量表在识别社区居住老年人的衰弱方面是可靠的,并且与衰弱表型相当,其优点是在临床环境中易于实施。识别社区居住老年人衰弱的可靠工具可能有助于提供及时干预以降低不良事件风险。