Wei Dan-Dan, Wan La-Gen, Deng Qiong, Liu Yang
Department of Bacteriology, First Affiliated Hospital of Nanchang University, Nanchang University, Yong wai zheng jie No. 17, Nanchang, 330006, PR China.
Department of Hospital Infection Control, First Affiliated Hospital of Nanchang University, Nanchang University, Yong wai zheng jie No. 17, Nanchang, 330006, PR China.
Diagn Microbiol Infect Dis. 2016 Jun;85(2):192-4. doi: 10.1016/j.diagmicrobio.2015.03.012. Epub 2015 Mar 21.
KPC-2 has been rarely reported in hypervirulent Klebsiella pneumoniae strains. Here, we describe a KPC-2-producing K. pneumoniae hypervirulent clone of capsular serotype K1 belonging to sequence type 11. The presence of KPC carbapenemase in hypervirulent clone could mark an evolutionary step toward its establishment as major nosocomial pathogen.
肺炎克雷伯菌碳青霉烯酶-2（KPC-2）在高毒力肺炎克雷伯菌菌株中鲜有报道。在此，我们描述了一株产KPC-2的肺炎克雷伯菌高毒力克隆株，其荚膜血清型为K1，序列型为11。高毒力克隆株中存在KPC碳青霉烯酶可能标志着其向成为主要医院感染病原体迈出了进化的一步。
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