Bays Harold, Kothari Shanu N, Azagury Dan E, Morton John M, Nguyen Ninh T, Jones Peter H, Jacobson Terry A, Cohen David E, Orringer Carl, Westman Eric C, Horn Deborah B, Scinta Wendy, Primack Craig
Louisville Metabolic and Atherosclerosis Research Center, Louisville, Kentucky.
Department of General Surgery, Gundersen Health System, La Crosse, Wisconsin.
Surg Obes Relat Dis. 2016 Mar-Apr;12(3):468-495. doi: 10.1016/j.soard.2016.01.007. Epub 2016 Jan 12.
Bariatric procedures generally improve dyslipidemia, sometimes substantially so. Bariatric procedures also improve other major cardiovascular risk factors. This 2-part Scientific Statement examines the lipid effects of bariatric procedures and reflects contributions from authors representing the American Society for Metabolic and Bariatric Surgery (ASMBS), the National Lipid Association (NLA), and the Obesity Medicine Association (OMA). Part 1 was published in the Journal of Clinical Lipidology, and reviewed the impact of bariatric procedures upon adipose tissue endocrine and immune factors, adipose tissue lipid metabolism, as well as the lipid effects of bariatric procedures relative to bile acids and intestinal microbiota. This Part 2 reviews: (1) the importance of nutrients (fats, carbohydrates, and proteins) and their absorption on lipid levels; (2) the effects of bariatric procedures on gut hormones and lipid levels; (3) the effects of bariatric procedures on nonlipid cardiovascular disease (CVD) risk factors; (4) the effects of bariatric procedures on lipid levels; (5) effects of bariatric procedures on CVD; and finally, (6) the potential lipid effects of vitamin, mineral, and trace element deficiencies, that may occur after bariatric procedures.
减肥手术通常能改善血脂异常,有时改善程度相当显著。减肥手术还能改善其他主要的心血管危险因素。这份分为两部分的科学声明探讨了减肥手术对血脂的影响,并反映了来自美国代谢与减肥外科学会(ASMBS)、国家脂质协会(NLA)和肥胖医学协会(OMA)的作者们所做的贡献。第一部分发表在《临床脂质学杂志》上,回顾了减肥手术对脂肪组织内分泌和免疫因子、脂肪组织脂质代谢的影响,以及减肥手术相对于胆汁酸和肠道微生物群的脂质效应。第二部分回顾:(1)营养素(脂肪、碳水化合物和蛋白质)及其吸收对血脂水平的重要性;(2)减肥手术对肠道激素和血脂水平的影响;(3)减肥手术对非脂质心血管疾病(CVD)危险因素的影响;(4)减肥手术对血脂水平的影响;(5)减肥手术对心血管疾病的影响;最后,(6)减肥手术后可能出现的维生素、矿物质和微量元素缺乏对脂质的潜在影响。