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非酒精性脂肪性肝病与肥胖症:肥胖医学协会(OMA)2022年临床实践声明(CPS)

Nonalcoholic fatty liver disease and obesity: An Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) 2022.

作者信息

Karjoo Sara, Auriemma Anthony, Fraker Teresa, Bays Harold Edward

机构信息

University of South Florida, 12901 Bruce B Downs Blvd, Tampa, FL, 33612, USA.

Florida State University, 1115 W Call St., Tallahassee, FL, 32304, USA.

出版信息

Obes Pillars. 2022 Jul 8;3:100027. doi: 10.1016/j.obpill.2022.100027. eCollection 2022 Sep.

Abstract

BACKGROUND

This Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) provides clinicians an overview of nonalcoholic fatty liver disease (NAFLD), potential progression to nonalcoholic steatohepatitis (NASH), and their application to obesity.

METHODS

The scientific information for this CPS is based upon published scientific citations, clinical perspectives of OMA authors, and peer review by the Obesity Medicine Association leadership.

RESULTS

Topics of this CPS include the prevalence of NAFLD and NASH, the prevalence of NAFLD and NASH among patients with obesity, as well as NAFLD and NASH definitions, diagnosis, imaging, pathophysiology, differential diagnosis, role of high fructose corn syrup and other simple sugars, and treatment (e.g., nutrition, physical activity, medications).

CONCLUSIONS

This Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) regarding NAFLD and obesity is one of a series of OMA CPSs designed to assist clinicians in the care of patients with the disease of obesity. Patients with obesity are at increased risk for NAFLD and NASH. Patients may benefit when clinicians who manage obesity understand the etiology, diagnosis, and optimal treatment of NAFLD with a goal to prevent NASH.

摘要

背景

本肥胖医学协会(OMA)临床实践声明(CPS)为临床医生提供了非酒精性脂肪性肝病(NAFLD)、向非酒精性脂肪性肝炎(NASH)潜在进展及其在肥胖症中的应用的概述。

方法

本CPS的科学信息基于已发表的科学引文、OMA作者的临床观点以及肥胖医学协会领导层的同行评审。

结果

本CPS的主题包括NAFLD和NASH的患病率、肥胖症患者中NAFLD和NASH的患病率,以及NAFLD和NASH的定义、诊断、影像学、病理生理学、鉴别诊断、高果糖玉米糖浆和其他单糖的作用以及治疗(如营养、体育活动、药物治疗)。

结论

本肥胖医学协会(OMA)关于NAFLD和肥胖症的临床实践声明(CPS)是OMA CPS系列之一,旨在帮助临床医生护理肥胖症患者。肥胖症患者患NAFLD和NASH的风险增加。当管理肥胖症的临床医生了解NAFLD的病因、诊断和最佳治疗方法以预防NASH时,患者可能会受益。

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