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糖尿病眼部筛查项目中增殖性糖尿病视网膜病变转诊延迟会导致视力丧失吗?

Does delay in referral of proliferative diabetic retinopathy from the diabetic eye screening programme lead to visual loss?

作者信息

Negretti G S, Amin R, Webster L, Egan C A

机构信息

Moorfields Eye Hospital NHS Foundation Trust, London, UK.

出版信息

Eye (Lond). 2016 Jun;30(6):873-6. doi: 10.1038/eye.2016.56. Epub 2016 Apr 8.

DOI:10.1038/eye.2016.56
PMID:27055673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4906462/
Abstract

AimsTo ascertain the effect on visual acuity (VA) of a delay in Hospital Eye Service (HES) consultation for patients referred with proliferative diabetic retinopathy (PDR; R3) from the Diabetic Eye Screening Programme (DESP).MethodsAll patients referred to Moorfields Eye Hospital from DESP between April and December 2013 with a referral diagnosis of PDR in at least one eye were eligible. Screening programme VA was compared with VA at first HES appointment and final follow-up appointment. Reasons for any VA loss were noted.ResultsA total of 86 patients were included. Of these, 28 (33%) were seen in more than 4 weeks after their DESP referral. At first HES appointment, 39 (45%) patients were graded as having active PDR in at least one eye. Delay in referral did not significantly predict the likelihood of vision loss in all patients referred (χ(2), P=0.49) or in just those patients with a definitive HES diagnosis of active PDR (χ(2), P=1.00). In only 3 patients with active PDR was a delay in presentation thought to have led directly to VA loss.ConclusionsThere may be minimal short-term visual consequence in several weeks of delayed referral for many patients with a diagnosis of R3. However, the national guidance remains important. This is due to the occasional patient at very high risk of vision loss and the many gains for the patients in terms of time to properly assess medical and ocular conditions and counsel and consent them for treatment where necessary.

摘要

目的

确定糖尿病视网膜病变筛查项目(DESP)转诊的增殖性糖尿病视网膜病变(PDR;R3)患者延迟接受医院眼科服务(HES)会诊对视力(VA)的影响。

方法

所有在2013年4月至12月期间从DESP转诊至摩尔菲尔德眼科医院、至少一只眼睛转诊诊断为PDR的患者均符合条件。将筛查项目时的视力与首次HES会诊及最终随访会诊时的视力进行比较。记录任何视力丧失的原因。

结果

共纳入86例患者。其中,28例(33%)在DESP转诊后4周以上才接受会诊。在首次HES会诊时,39例(45%)患者至少一只眼睛被分级为患有活动性PDR。转诊延迟并未显著预测所有转诊患者视力丧失的可能性(χ²,P = 0.49),也未显著预测那些被HES明确诊断为活动性PDR的患者视力丧失的可能性(χ²,P = 1.00)。仅3例活动性PDR患者的就诊延迟被认为直接导致了视力丧失。

结论

对于许多诊断为R3的患者,转诊延迟数周可能在短期内对视力影响极小。然而,国家指南仍然很重要。这是因为偶尔会有患者视力丧失风险极高,而且从时间方面来看,对患者有诸多益处,包括能够适当地评估医疗和眼部状况,并在必要时为他们提供咨询以及同意接受治疗。

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