Mascia A, Frank S, Berkman A, Stern L, Lampl L, Davies M, Yeager T, Birmaher B, Chieco E
Blythedale Children's Hospital, Valhalla, New York.
Ann Allergy. 1989 Apr;62(4):311-7.
Improved outcome (1 to 10 years) of 140 asthmatic children retrospectively correlated with 8 of 49 variables in admission evaluation: (1) age of onset, (2) IgE, (3) night/early AM bronchospasm, (4) aggression, (5) severely disrupted family circumstances, (6) severe psychopathology, (7) psychotic signs, and (8) I.Q. Patients with fatal outcome (6% to 12%) deviated in the last three variables; most were 12.1 to 16.5 years, male, Black/Hispanic, aggressive, depressed and/or anxious. Clinical implications include high-risk identification on the basis of psychologic and physiologic variables, preventative measures, and consideration of residential treatment.
对140名哮喘儿童（1至10年）改善的预后与入院评估中49项变量中的8项进行回顾性关联：（1）发病年龄，（2）免疫球蛋白E，（3）夜间/清晨支气管痉挛，（4）攻击性，（5）家庭环境严重混乱，（6）严重精神病理学，（7）精神病体征，以及（8）智商。有致命预后的患者（6%至12%）在最后三项变量上存在偏差；大多数为12.1至16.5岁，男性，黑人/西班牙裔，有攻击性，抑郁和/或焦虑。临床意义包括基于心理和生理变量进行高危识别、预防措施以及考虑住院治疗。
