Gandhi Ashok, Sundar I Vijay, Sharma Achal, Mittal R S, Gandhi Sapna
Department of Neurosurgery, SMS Medical College and Hospital, Jaipur, Rajasthan, India.
Department of Pathology, SMS Medical College and Hospital, Jaipur, Rajasthan, India.
Asian J Neurosurg. 2016 Apr-Jun;11(2):178. doi: 10.4103/1793-5482.145344.
Nasofrontal dermoid with sinus tract extending to the nasal tip is rare in adults. It is unique in its embryological origin, presentation, and management. Pathogenesis involves the incomplete obliteration of the developing neuroectoderm. A sinus opening with intermittent oily discharge is characteristic. Associated intracranial extension may lead to meningitis and brain abscess. We present a case of a 21-year-old adult having a nasofrontal sinus tract with intracranial extension who presented with recurrent episodes of meningitis and discuss the physical findings with relevance to embryology, elaborating on the importance and means of addressing the intracranial as well as extracranial components for complete treatment.
伴有延伸至鼻尖的窦道的鼻额部皮样囊肿在成人中较为罕见。其在胚胎起源、临床表现及治疗方面都独具特色。发病机制涉及发育中的神经外胚层未完全闭塞。特征性表现为有间歇性油性分泌物排出的窦口。相关的颅内延伸可能导致脑膜炎和脑脓肿。我们报告一例21岁成人患有伴有颅内延伸的鼻额窦道,该患者反复发生脑膜炎,并结合胚胎学讨论体格检查结果,详细阐述针对颅内及颅外部分进行完整治疗的重要性及方法。