Suna Nuretdin, Parlak Erkan, Kuzu Ufuk Baris, Yildiz Hakan, Koksal Aydin Seref, Oztas Erkin, Sirtas Zeliha, Yuksel Mahmut, Aydinli Onur, Bilge Zulfikar, Taskiran Ismail, Sasmaz Nurgul
From the Department of Gastroenterology, the Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara (NS, UBK, HY, EO, ZS, MY, OA, ZB, IT, NS), and Department of Gastroenterology, Sakarya University Medical School, (EP, ASK), Sakarya, Turkey.
Medicine (Baltimore). 2016 Apr;95(14):e3313. doi: 10.1097/MD.0000000000003313.
At present, we do not know the exact prevalence of Barrett esophagus (BE) developing later in patients without BE in their first endoscopic screening. The purpose of this study was to determine the prevalence of BE on the second endoscopic examination of patients who had no BE in their first endoscopic examination.The data of the patients older than 18 years who had undergone upper gastrointestinal system endoscopy more than once at the endoscopy unit of our clinic during the last 6 years were retrospectively analyzed.During the last 6 years, 44,936 patients had undergone at least one endoscopic examination. Among these patients, 2701 patients who had more than one endoscopic screening were included in the study. Of the patients, 1276 (47.3%) were females and 1425 (52.7%) were males, with an average age of 54.9 (18-94) years. BE was diagnosed in 18 (0.66%) of the patients who had no BE in the initial endoscopic examination. The patients with BE had reflux symptoms in their medical history and in both endoscopies, they revealed a higher prevalence of lower esophageal sphincter laxity, hiatal hernia, and reflux esophagitis when compared to patients without BE (P < 0.001).Our study showed that in patients receiving no diagnosis of BE on their first endoscopic examination performed for any reason, the prevalence of BE on their second endoscopy within 6 years was very low (0.66%).
目前，我们尚不清楚在首次内镜筛查时无巴雷特食管（BE）的患者中，BE在之后出现的确切患病率。本研究的目的是确定在首次内镜检查中无BE的患者进行第二次内镜检查时BE的患病率。对过去6年内在我们诊所内镜科接受过不止一次上消化道系统内镜检查的18岁以上患者的数据进行了回顾性分析。在过去6年中，44936名患者至少接受了一次内镜检查。在这些患者中，2701名接受了不止一次内镜筛查的患者被纳入研究。其中，女性1276名（47.3%），男性1425名（52.7%），平均年龄54.9岁（18 - 94岁）。在初次内镜检查时无BE的患者中，有18名（0.66%）被诊断为BE。有BE的患者在病史中存在反流症状，并且在两次内镜检查中，与无BE的患者相比，他们的食管下括约肌松弛、食管裂孔疝和反流性食管炎的患病率更高（P < 0.001）。我们的研究表明，因任何原因在首次内镜检查时未被诊断为BE的患者，在6年内进行第二次内镜检查时BE的患病率非常低（0.66%）。
