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斑秃与发作性睡病:一个关于隐匿性自身免疫的故事。

Alopecia areata and narcolepsy: a tale of obscure autoimmunity.

作者信息

Nigam Gaurav, Pathak Charu, Riaz Muhammad

机构信息

University of Michigan, Ann Arbor, Michigan, USA.

NSCB Medical College, Jabalpur, India.

出版信息

BMJ Case Rep. 2016 Apr 8;2016:bcr2015211523. doi: 10.1136/bcr-2015-211523.

Abstract

Alopecia areata is an autoimmune dermatological disorder characterised by loss of hair in one or more discrete patches over the scalp. It has been linked to multiple disorders having an autoimmune origin. Like many autoimmune disorders it tends to be more common in females. To date, only five cases have been reported where alopecia has been associated with narcolepsy. Male gender is less commonly affected by alopecia areata. No case of alopecia areata in males has been associated with narcolepsy to the best of our knowledge. The current case represents the first ever-reported case of alopecia areata in a male patient with narcolepsy type 1. This coexistence is most likely the manifestation of a common underlying pathoimmunological mechanism that has not been completely understood, rather than a random association.

摘要

斑秃是一种自身免疫性皮肤病,其特征是头皮上出现一个或多个离散的脱发斑。它与多种自身免疫性起源的疾病有关。与许多自身免疫性疾病一样,它在女性中往往更为常见。迄今为止,仅报告了5例斑秃与发作性睡病相关的病例。男性较少受到斑秃的影响。据我们所知,没有男性斑秃病例与发作性睡病相关。本病例是首例报告的1型发作性睡病男性患者合并斑秃的病例。这种共存很可能是一种尚未完全理解的共同潜在病理免疫机制的表现,而非随机关联。

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本文引用的文献

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[Narcolepsy and alopecia areata: a new association?].
An Med Interna. 1992 May;9(5):234-6.

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