儿童急性淋巴细胞白血病中原始细胞大小与首次缓解期长度之间缺乏相关性。

Lack of correlation between blast cell size and length of first remission in acute lymphocytic leukemia in childhood.

作者信息

Wagner V M, Baehner R L

出版信息

Med Pediatr Oncol. 1977;3(4):373-7. doi: 10.1002/mpo.2950030408.

Abstract

The bone marrow from 55 children with acute lymphocytic leukemia diagnosed from April 1969 to June 1973 were evaluated for blast cell morphology and size. Sixteen marrows contained a predominance of macrolymphoblasts (greater than 12 mu), while the remainder contained mainly microlymphoblasts. There was no correlation between blast cell size and the known front-end prognostic indicators of age and initial white blood count, nor could blast cell size be used to predict the length of initial bone marrow remission.

摘要

对1969年4月至1973年6月诊断为急性淋巴细胞白血病的55名儿童的骨髓进行了原始细胞形态和大小评估。16份骨髓中以大原始淋巴细胞为主（大于12微米），其余主要为小原始淋巴细胞。原始细胞大小与已知的年龄和初始白细胞计数等前期预后指标之间没有相关性，原始细胞大小也不能用于预测初始骨髓缓解期的长短。