Sulfaro S, Barzan L, Querin F, Lutman M, Caruso G, Comoretto R, Volpe R, Carbone A
Division of Pathology, Centro di Riferimento Oncologico, Aviano, Italy.
Arch Otolaryngol Head Neck Surg. 1989 May;115(5):613-20. doi: 10.1001/archotol.1989.01860290071017.
Sixty-six whole-organ sectioned, nonirradiated, laryngopharyngectomy specimens that were removed because of cancer during a 7-year period were uniformly examined to determine the accuracy of perioperative T staging by high-resolution computed tomography (CT) and clinical evaluation (indirect-direct laryngoscopy) by comparing this preoperative staging with the postsurgical pathologic staging. The accuracy of the clinical vs CT staging for laryngeal carcinomas was 58.8% vs 70.6%, whereas the accuracy of the staging by combination of the two modalities was 88.2%. Combined staging modalities showed the same accuracy for laryngeal and hypopharyngeal carcinomas (88.2%), whereas clinical staging accuracy for hypopharyngeal carcinomas was lower (52.9%) and CT accuracy was higher (82.4%) than that observed for laryngeal carcinomas. In the majority of the cases that were staged inaccurately, the error was one of under-estimation: in particular, tumors confined to the mucosa and early infiltration of laryngeal fat spaces were not detected by CT.
对66份在7年期间因癌症而切除的全器官切片、未接受过放疗的喉咽切除术标本进行了统一检查，通过将术前分期与术后病理分期进行比较，以确定高分辨率计算机断层扫描（CT）进行围手术期T分期的准确性以及临床评估（间接-直接喉镜检查）的准确性。喉癌临床分期与CT分期的准确率分别为58.8%和70.6%，而两种方法联合分期的准确率为88.2%。联合分期方法对喉癌和下咽癌的准确率相同（88.2%），而下咽癌的临床分期准确率较低（52.9%），CT准确率较高（82.4%），高于喉癌。在大多数分期不准确的病例中，错误是低估：特别是，CT未检测到局限于黏膜的肿瘤和喉脂肪间隙的早期浸润。
