Knox R, Pratt M, Garvin A J, White B
Department of Otolaryngology and Communicative Sciences, Medical University of South Carolina, Charleston 29425.
Arch Otolaryngol Head Neck Surg. 1989 May;115(5):630-2. doi: 10.1001/archotol.1989.01860290088021.
Heterotopic brain is a rare entity. Histologically, this lesion resembles mature brain and often contains specialized tissues similar to choroid plexus or glia. Specialized neural stains are necessary to differentiate this rare anomaly from other tumors or conditions found in the head and neck. The differential diagnosis includes squamous cell carcinoma, granular cell tumor, hemangioma, lymphangioma, thyroglossal duct cyst, dermoid cyst, hamartoma, rhabdomyosarcoma, and teratoma. We describe a newborn with heterotopic brain tissue occurring on the dorsum of the tongue. We found only one other description of this developmental aberration in the English literature. Our patient was successfully treated with carbon dioxide laser excision of the mass. There has been no evidence of complication or recurrence after one year of follow-up.
异位脑是一种罕见的病变。从组织学上看，这种病变类似于成熟脑，且常包含类似于脉络丛或神经胶质的特殊组织。需要使用特殊的神经染色来将这种罕见的异常与头颈部发现的其他肿瘤或病症区分开来。鉴别诊断包括鳞状细胞癌、颗粒细胞瘤、血管瘤、淋巴管瘤、甲状舌管囊肿、皮样囊肿、错构瘤、横纹肌肉瘤和畸胎瘤。我们描述了一名新生儿，其舌背出现异位脑组织。我们在英文文献中仅发现了另外一篇关于这种发育异常的描述。我们的患者通过二氧化碳激光切除肿块获得了成功治疗。随访一年后，没有并发症或复发的迹象。
