Ramachandra V, Moore C, Kaur N, Carli F
Department of Anaesthesia, Northwick Park Hospital, Harrow.
Br J Anaesth. 1989 Apr;62(4):409-14. doi: 10.1093/bja/62.4.409.
The superficial and deep body temperatures of 40 healthy females undergoing total abdominal hysterectomy were measured during surgery and for 4 h afterwards. The patients were allocated randomly to one of five groups and anaesthetized to produce an end-tidal concentration of 1% halothane, 1% enflurane, 2% enflurane, 1% isoflurane or 2% isoflurane. The patients received also 70% nitrous oxide in oxygen and neuromuscular blockade. The theatre temperature was maintained at 22.0 degrees C. There were significant body temperature changes during operation in all groups. The mean (SD) decrease in core temperature over 85 min was approximately 1.1 (0.3) degrees C in the 1% halothane, 2% enflurane and 2% isoflurane groups, and 0.6 (0.4) degrees C in the 1% enflurane and 1% isoflurane groups (P less than 0.05). During the recovery period the 1% halothane, 2% enflurane and 2% isoflurane groups took 2 h to rewarm to preoperative temperatures, and the rate of rewarming during this time was similar for all groups.
对40例行全腹子宫切除术的健康女性，在手术期间及术后4小时测量其体表和深部体温。患者被随机分配到五组中的一组，麻醉诱导使呼气末氟烷浓度达1%、恩氟烷浓度达1%、恩氟烷浓度达2%、异氟烷浓度达1%或异氟烷浓度达2%。患者还接受70%氧化亚氮与氧气混合气体及神经肌肉阻滞剂。手术室温度维持在22.0℃。所有组在手术过程中体温均有显著变化。1%氟烷、2%恩氟烷和2%异氟烷组在85分钟内核心体温平均（标准差）下降约1.1（0.3）℃，1%恩氟烷和1%异氟烷组下降0.6（0.4）℃（P<0.05）。在恢复期，1%氟烷、2%恩氟烷和2%异氟烷组需要2小时恢复到术前体温，且在此期间所有组的复温速率相似。
