Morrison Julie L, Hodgson Lauren Ab, Lim Lyndell L, Al-Qureshi Salmaan
Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.
Division of Ophthalmology, Department of Surgery, University of Melbourne, Melbourne, Victoria, Australia.
Clin Exp Ophthalmol. 2016 May;44(4):321-34. doi: 10.1111/ceo.12760. Epub 2016 May 17.
The prevalence of diabetes in pregnancy is increasing. Pre-existing diabetes is present in 1 in 167 pregnancies in Australia, divided equally between type 1 and type 2 diabetes. Diabetic retinopathy is a leading cause of blindness in women during their childbearing years, and pregnancy increases the short-term risk of diabetic retinopathy progression. We examine the risk factors for progression of diabetic retinopathy during pregnancy including duration of diabetes, baseline level of retinopathy, level of glycaemic control and hypertension. We also examine current screening and management guidelines and their levels of evidence, current treatment options for diabetic retinopathy and avenues for further research.
妊娠期糖尿病的患病率正在上升。在澳大利亚,每167次妊娠中就有1例存在孕前糖尿病,1型糖尿病和2型糖尿病的比例相等。糖尿病视网膜病变是育龄妇女失明的主要原因,而怀孕会增加糖尿病视网膜病变进展的短期风险。我们研究了妊娠期糖尿病视网膜病变进展的风险因素,包括糖尿病病程、视网膜病变的基线水平、血糖控制水平和高血压。我们还研究了当前的筛查和管理指南及其证据水平、糖尿病视网膜病变的当前治疗选择以及进一步研究的途径。