Department of Physiology, College of Korean Medicine, Daegu Haany University, Daegu 706-828, South Korea.
Department of Acupuncture and Moxibustion, College of Korean Medicine, Daegu Haany University, Daegu 706-828, South Korea.
Complement Ther Med. 2016 Apr;25:27-33. doi: 10.1016/j.ctim.2015.12.021. Epub 2016 Jan 6.
The adequate treatment of spinal cord injury (SCI)-induced neuropathic pain still remains an unresolved problem. The current medications predominantly used in the SCI-induced neuropathic pain therapy are morphine, anticonvulsants, antidepressants, and antiepileptics, which suggests that psychiatric aspects might be important factors in the treatment of neuropathic pain. It is well documented that the modulation of the sensory events is not a unique way for achieving pain relief. In addition, pain patients still express dissatisfaction and complain of unwanted effects of the medications, suggesting that alternative approaches for the treatment of neuropathic pain are essential. In psychiatry, pain relief represents relaxation and a feeling of comfort and satisfaction, which suggests that cognitive and emotional motivations are important factors in the treatment of neuropathic pain. The comorbidity of chronic pain and psychiatric disorders, which is well recognized, suggests that the effective therapeutic relief for neuropathic pain induced by SCI can be achieved in conjunction with the management of the sensory and psychiatric aspects of patient. In this review, we address the feasibility of a combined acupuncture and pharmacotherapy treatment for the relief of neuropathic pain behavior following SCI.
脊髓损伤（SCI）引起的神经性疼痛的充分治疗仍然是一个未解决的问题。目前主要用于 SCI 诱导的神经性疼痛治疗的药物是吗啡、抗惊厥药、抗抑郁药和抗癫痫药，这表明精神方面可能是治疗神经性疼痛的重要因素。有充分的文献记载表明，感觉事件的调节并不是缓解疼痛的唯一方法。此外，疼痛患者仍然表示不满，并抱怨药物的不良反应，这表明治疗神经性疼痛需要替代方法。在精神病学中，缓解疼痛代表放松和舒适满足的感觉，这表明认知和情感动机是治疗神经性疼痛的重要因素。慢性疼痛和精神障碍的共病是众所周知的，这表明可以通过管理 SCI 引起的神经性疼痛患者的感觉和精神方面来实现对神经性疼痛的有效治疗缓解。在这篇综述中，我们探讨了针灸和药物治疗相结合治疗 SCI 后神经性疼痛行为的可行性。
