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自身免疫病因引起的喉气管狭窄

Laryngotracheal stenosis of autoimmune aetiology.

作者信息

Dablanca Maria, Maeso Ana, Méndez Desiree Del C, Ortega Primitivo

机构信息

Hospital Universitario de Móstoles, Madrid, España.

Hospital Universitario de Móstoles, Madrid, España.

出版信息

Acta Otorrinolaringol Esp. 2017 Jan-Feb;68(1):38-42. doi: 10.1016/j.otorri.2016.01.002. Epub 2016 Apr 8.

Abstract

Autoimmune origin ranks fifth in the etiologic classification of laryngotracheal stenosis. Wegener's disease is the autoimmune illness most associated with stenosis; however, there are other autoimmune diseases that may also be associated with it. A descriptive, retrospective study of 9 cases of laryngotracheal stenosis associated with autoimmune disease was carried out. There were 9 patients (8 females and 1 male) with an average age of 27.9 years. Four of the patients suffered from Wegener's disease, 1 from ulcerative colitis and 1 from purple vasculitis. The other 3 patients only had positive c-ANA. Endoscopic treatment was performed in 3 cases. The other 6 patients required open surgery. Respiratory results were acceptable. Based on our study, we feel that the immunological profiles should be studied in all patients with stenosis, given that not only Wegener's disease is linked to stenosis.

摘要

自身免疫起源在喉气管狭窄的病因分类中排名第五。韦格纳肉芽肿病是与狭窄最相关的自身免疫性疾病;然而,还有其他自身免疫性疾病也可能与之相关。对9例与自身免疫性疾病相关的喉气管狭窄病例进行了描述性回顾性研究。有9名患者(8名女性和1名男性),平均年龄27.9岁。其中4例患者患有韦格纳肉芽肿病,1例患有溃疡性结肠炎,1例患有紫癜性血管炎。其他3例患者仅c-ANA呈阳性。3例患者接受了内镜治疗。其他6例患者需要进行开放性手术。呼吸结果尚可。基于我们的研究,我们认为鉴于不仅韦格纳肉芽肿病与狭窄有关,所有狭窄患者都应研究其免疫学特征。

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