静脉注射普萘洛尔用于控制危重新生儿的大型头颈部血管瘤
Use of intravenous propranolol for control of a large cervicofacial hemangioma in a critically ill neonate.
作者信息
Fernando Shanik J, Leitenberger Sabra, Majerus Matt, Krol Alfons, MacArthur Carol J
机构信息
Department of Otolaryngology - Head and Neck Surgery, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, PV01, Portland, OR 97239, USA; School of Medicine, Vanderbilt University, 201 Light Hall, 2215 Garland Avenue, Nashville, TN 37232, USA.
Department of Dermatology, Oregon Health & Science University, Center for Health & Healing, Mail code: CH16D, 3303 SW Bond Avenue, Portland, OR 97239, USA.
出版信息
Int J Pediatr Otorhinolaryngol. 2016 May;84:52-4. doi: 10.1016/j.ijporl.2016.02.005. Epub 2016 Feb 12.
Cervicofacial segmental infantile hemangiomas (IH) may result in airway obstruction requiring use of propranolol to induce hemangioma regression and reestablish the airway. We present the first case using intravenous (IV) propranolol for control of airway obstruction and rapid expansion of cervicofacial IH in the setting of necrotizing enterocolitis (NEC) impaired gastrointestinal function. Intravenous dosing of propranolol was tolerated well in a critically ill neonate with multisystem complications of prematurity.
头颈部节段性婴儿血管瘤（IH）可能导致气道阻塞，需要使用普萘洛尔来促使血管瘤消退并重建气道。我们报告了首例在坏死性小肠结肠炎（NEC）导致胃肠功能受损的情况下，使用静脉注射（IV）普萘洛尔控制气道阻塞并使头颈部IH迅速消退的病例。静脉注射普萘洛尔在一名患有早产多系统并发症的危重新生儿中耐受性良好。
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