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一例罕见的小儿后三角区非创伤性骨化性肌炎病例。

A rare case of pediatric Nontraumatic Myositis Ossificans in the posterior triangle.

作者信息

Simmonds Jonathan, Taki Nizar, Chilton Ilana, Vecchiotti Mark

机构信息

Department of Pediatric Otolaryngology, Floating Hospital for Children, Tufts Medical Center, Boston, MA, United States.

Department of Pathology, Floating Hospital for Children, Tufts Medical Center, Boston, MA, United States.

出版信息

Int J Pediatr Otorhinolaryngol. 2016 May;84:116-8. doi: 10.1016/j.ijporl.2016.03.003. Epub 2016 Mar 12.

Abstract

BACKGROUND

Myositis Ossificans Cicumscripta is a rare condition characterized by aberrant bone formation in paramuscular soft tissue of the extremities usually associated with trauma or a genetic mutation. Very few cases involve the head or neck and it is rarely found in the pediatric population.

OBJECTIVES

We present a case of a 5-month old with a rapidly growing posterior neck mass suspicious for neoplasia, which was treated with surgical resection and found to be a non-traumatic, non-genetic form of Myositis Ossificans. The workup, treatment, and findings of the patient are outlined and a review of the literature on this disease is discussed.

CONCLUSION

Myositis Ossificans is characterized by aberrant bone formation typically occurring after trauma but may be secondary to an underlying genetic abnormality. The case presented in the absence of trauma or an underlying genetic abnormality and is therefore an exceedingly rare instance of the sporadic form that presented spontaneously in the head and neck of a pediatric patient.

摘要

背景

局限性骨化性肌炎是一种罕见病症,其特征为四肢肌肉旁软组织中出现异常骨形成,通常与创伤或基因突变有关。极少病例累及头颈部,在儿科人群中也很少见。

目的

我们报告一例5个月大的患儿,其颈部后方有一个迅速增大的肿物,怀疑为肿瘤,经手术切除后发现是一种非创伤性、非遗传性的骨化性肌炎。概述了该患者的检查、治疗及结果,并讨论了关于这种疾病的文献综述。

结论

骨化性肌炎的特征是异常骨形成,通常发生在创伤后,但也可能继发于潜在的基因异常。本病例在无创伤或潜在基因异常的情况下出现,因此是小儿患者头颈部自发出现的散发性形式的极为罕见的实例。

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