Akhter M Siddique J, Verma R, Madhukar K Premjeet, Vaishampayan A Rajiv, Unadkat P C
General Surgery, Senior Resident.
General Surgery, Professor, Head Of Unit.
J Wound Care. 2016 Apr;25(4):210-2, 214-7. doi: 10.12968/jowc.2016.25.4.210.
A prospective observational was carried out to calculate the incidence of surgical site infections (SSI) along with the main risk factors and causative organisms in postoperative patients at a tertiary care setting in Mumbai.
A total number of 1196 patients between June 2011 to March 2013 admitted to the general surgical ward or surgical ICU of our hospital were included in the study. Post laproscopy patients and organ space SSIs were excluded. Patient data were collected using a preformed pro forma and a wound Southampton score tabulated and checked repeatedly until suture removal of patient. Regular follow-up was maintained until at least 30 days postoperatively.
The study showed a SSI rate of 11%. Risk factors associated with a higher incidence of SSI were found to be age (>55 years), diabetes mellitus (especially uncontrolled sugar in the perioperative period), immunocompromised patients (mainly HIV and immunosuppressive therapy patients), surgeon skill (higher in senior professors compared with junior residents), nature of the cases, (emergency surgeries), placement of drains, wound class (highest in dirty wounds), type of closure (multilayer closure), prolonged duration of hospital stay, longer duration of surgery (>2 hours), type of surgery (highest in cholecystectomy). The highest rates of causative organisms for SSIs found were Staphylococcus aureus, Escherichia coli and Klebsiella ssp.
Prevention of SSIs requires a multipronged approach with particular emphasis on optimising preoperative issues, adhering religiously to strict protocols during the intraoperative period and addressing and optimising metabolic and nutritional status in postoperative period.
在孟买的一家三级医疗机构中,开展一项前瞻性观察研究,以计算手术部位感染(SSI)的发生率以及术后患者的主要风险因素和致病微生物。
本研究纳入了2011年6月至2013年3月期间入住我院普通外科病房或外科重症监护病房的1196例患者。排除腹腔镜术后患者和器官间隙SSI患者。使用预先制定的表格收集患者数据,并将伤口南安普顿评分制成表格,在患者拆线前反复检查。术后至少维持30天的定期随访。
研究显示SSI发生率为11%。发现与SSI发生率较高相关的风险因素包括年龄(>55岁)、糖尿病(尤其是围手术期血糖控制不佳)、免疫功能低下患者(主要是艾滋病毒感染者和接受免疫抑制治疗的患者)、外科医生技能(与低年资住院医师相比, senior professors的发生率更高)、病例性质(急诊手术)、引流管放置、伤口类别(污染伤口中最高)、缝合类型(多层缝合)、住院时间延长、手术时间延长(>2小时)、手术类型(胆囊切除术中最高)。发现的SSI致病微生物发生率最高的是金黄色葡萄球菌、大肠杆菌和克雷伯菌属。
预防SSI需要采取多管齐下的方法,特别强调优化术前问题、在术中严格遵守严格的方案以及在术后解决和优化代谢及营养状况。