蛋白质合成抑制剂对3T3细胞铺展速率的刺激作用。
Stimulatory effects of protein synthesis inhibitors on the spreading rate of 3T3 cells.
作者信息
Verger C, Petrovic M, Imbenotte J
机构信息
C.N.R.S., Villejuif, France.
出版信息
Cell Biol Int Rep. 1989 Mar;13(3):231-5. doi: 10.1016/0309-1651(89)90145-8.
PMID:2706685
Abstract
Three protein synthesis inhibitors, puromycin, cycloheximide and anisomycin were found to increase the rate of spreading of Swiss-3T3 cells after 1 h incubation in the presence of low concentrations of serum. Data from experiments with anisomycin suggest that this effect is roughly proportional to the extent of inhibition of protein synthesis.
摘要
在低浓度血清存在的情况下孵育1小时后，发现三种蛋白质合成抑制剂，即嘌呤霉素、环己酰亚胺和茴香霉素，可提高瑞士3T3细胞的铺展速率。用茴香霉素进行的实验数据表明，这种效应大致与蛋白质合成的抑制程度成正比。
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