Faure Elsa Madeleine, Canaud Ludovic, Marty-Ané Charles, Alric Pierre
Department of Vascular and Thoracic Surgery, Arnaud de Villeneuve Hospital, Montpellier, France.
Department of Vascular and Thoracic Surgery, Arnaud de Villeneuve Hospital, Montpellier, France.
J Thorac Cardiovasc Surg. 2016 Jul;152(1):162-8. doi: 10.1016/j.jtcvs.2016.03.020. Epub 2016 Mar 12.
This study analyzed the outcome of a combined endovascular and debranching procedure for hybrid aortic arch repair in patients with chronic dissecting aortic aneurysms involving the aortic arch.
We reviewed all consecutive patients who underwent hybrid aortic arch repair for dissecting aneurysm at the Arnaud de Villeneuve Hospital.
A total of 33 consecutive patients between March 2005 and September 2015 were included. Patients' mean age was 65.1 ± 12.2 years. Mean aneurysm diameter was 60.3 ± 14.2 mm. Patients were treated for aneurysm diameter 55 mm or greater (n = 28), aortic growth more than 1 cm/year (n = 3), or rupture (n = 2). Eleven complete supra-aortic debranchings were performed in zone 0, with 2 concomitant replacements of the ascending aorta. Partial aortic arch debranching was performed in 22 patients (zone 1 = 8; zone 2 = 14). Technical success was achieved in 97% of patients. There was no in-hospital death. One patient died of decompensated cirrhosis on day 20, resulting in a 30-day mortality of 3%. One patient had major cerebrovascular complications (3%). Spinal cord ischemia was observed in 1 patient (3%), with complete recovery after spinal fluid drainage. Retrograde dissection occurred in 1 patient (3%). After a mean follow-up of 24.3 months (range, 0.6-104.8 months), the overall mortality was 12% (n = 4) with 3 additional deaths. Endoleak was reported in 6 patients (18%), of whom 2 required reintervention. Overall, 8 reinterventions were performed (24%), with a mean time from intervention of 8.7 months (range, 1.2-24.6 months).
Hybrid aortic arch repair for dissecting aneurysm is associated with acceptable early and midterm major morbidity and mortality, even for patients treated in zone 0. However, given the high rate of reintervention and endoleak, close follow-up is required.
本研究分析了血管腔内与去分支手术联合治疗累及主动脉弓的慢性主动脉夹层动脉瘤的杂交主动脉弓修复术的疗效。
我们回顾了在阿诺·德·维勒纳夫医院接受杂交主动脉弓修复术治疗夹层动脉瘤的所有连续患者。
纳入了2005年3月至2015年9月期间的33例连续患者。患者的平均年龄为65.1±12.2岁。动脉瘤平均直径为60.3±14.2mm。患者因动脉瘤直径55mm或更大(n=28)、主动脉每年增长超过1cm(n=3)或破裂(n=2)而接受治疗。在0区进行了11次完全性主动脉弓上分支去分支术,其中2例同时进行了升主动脉置换。22例患者进行了部分主动脉弓去分支术(1区=8例;2区=14例)。97%的患者手术技术成功。无院内死亡。1例患者在第20天死于失代偿性肝硬化,30天死亡率为3%。1例患者发生严重脑血管并发症(3%)。1例患者出现脊髓缺血(3%),经脑脊液引流后完全恢复。1例患者发生逆行夹层(3%)。平均随访24.3个月(范围0.6 - 104.8个月)后,总死亡率为12%(n = 4),另有3例死亡。6例患者(18%)报告有内漏,其中2例需要再次干预。总体而言,进行了8次再次干预(24%),再次干预的平均时间为8.7个月(范围1.2 - 24.6个月)。
即使是在0区接受治疗的患者,杂交主动脉弓修复术治疗夹层动脉瘤的早期和中期主要发病率和死亡率也可接受。然而,鉴于再次干预和内漏的发生率较高,需要密切随访。