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体外冲击波疗法与透明质酸注射治疗疼痛性非钙化性肩袖肌腱病的初步结果

Extracorporeal shockwaves therapy versus hyaluronic acid injection for the treatment of painful non-calcific rotator cuff tendinopathies: preliminary results.

作者信息

Frizziero Antonio, Vittadini Filippo, Barazzuol Michele, Gasparre Giuseppe, Finotti Paolo, Meneghini Andrea, Maffulli Nicola, Masiero Stefano

机构信息

Department of Physical and Rehabilitation Medicine, University of Padua, Padua, Italy -

Department of Physical and Rehabilitation Medicine, University of Padua, Padua, Italy.

出版信息

J Sports Med Phys Fitness. 2017 Sep;57(9):1162-1168. doi: 10.23736/S0022-4707.16.06408-2. Epub 2016 Apr 12.

Abstract

BACKGROUND

Rotator cuff tendinopathy is the most common cause of painful shoulder. The treatment is mainly conservative and several therapeutic approaches have been proposed, including NSAIDs, physiotherapy, injections and physical therapies. The aim of the current study was to compare the clinical effectiveness of low molecular weight hyaluronic acid (LMW-HA) injection versus low-energy extracorporeal shock-wave therapy (ESWT) until 3 months of follow-up for the management of painful non-calcific rotator cuff tendinopathies, evaluating also the trend over time between the groups.

METHODS

A total of 34 patients affected by painful rotator cuff tendinopathy were randomly divided into 2 groups of 17 individuals. The first group (group A; mean age 58.2 years) underwent 3 injections of LMW-HA (Hyalgan®, 500-730 kDa), while in the second group (group B; mean age 58.5 years) the treatment protocol consisted of 4 sessions of low-energy ESWT. Pain level and function were assessed with the DASH and Constant-Murley questionnaires. Parameters were evaluated at baseline (V0), at the end of the treatment (V1) and after 3 months of follow-up (V2).

RESULTS

Patients of both groups achieved statistically significant improve in pain and function (P<0.0001). Clinical outcome shows a different trend in time between group A and group B for DASH and Constant-Murley questionnaires.

CONCLUSIONS

LMW-HA and low-energy ESWT are effective and safe in patients suffering from non-calcific rotator cuff tendinopathy until 3 months of follow-up. Intra-articular injections of LMW-HA provide prompt clinical improvement compared to ESWT, which results in more gradual improvement over time.

摘要

背景

肩袖肌腱病是肩部疼痛最常见的原因。治疗主要是保守治疗,已经提出了几种治疗方法,包括非甾体抗炎药、物理治疗、注射和物理疗法。本研究的目的是比较低分子量透明质酸(LMW-HA)注射与低能量体外冲击波疗法(ESWT)在治疗非钙化性肩袖肌腱病至3个月随访期的临床疗效,并评估两组之间随时间的变化趋势。

方法

共有34例患有疼痛性肩袖肌腱病的患者被随机分为两组,每组17人。第一组(A组;平均年龄58.2岁)接受3次LMW-HA(施沛特®,500-730 kDa)注射,而第二组(B组;平均年龄58.5岁)的治疗方案包括4次低能量ESWT治疗。使用DASH和Constant-Murley问卷评估疼痛程度和功能。在基线(V0)、治疗结束时(V1)和随访3个月后(V2)评估参数。

结果

两组患者的疼痛和功能均有统计学意义的改善(P<0.0001)。对于DASH和Constant-Murley问卷,A组和B组的临床结果在时间上呈现出不同的趋势。

结论

在随访3个月内,LMW-HA和低能量ESWT对非钙化性肩袖肌腱病患者有效且安全。与ESWT相比,关节内注射LMW-HA可迅速改善临床症状,而ESWT随着时间的推移改善更为渐进。

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