Hess N Cl, Carlson D J, Inder J D, Jesulola E, McFarlane J R, Smart N A
School of Science and Technology, University of New England, Armidale, Australia.
Physiol Res. 2016 Jul 18;65(3):461-8. doi: 10.33549/physiolres.933120. Epub 2016 Apr 12.
There exists no examination of what is the minimum anti-hypertensive threshold intensity for isometric exercise training. Twenty two normotensive participants were randomly assigned to training intensities at either 5 % or 10 % of their maximal contraction. Twenty participants completed the study. Clinical meaningful, but not statistically significant, reductions in systolic blood pressure were observed in both 5 % and 10 % groups -4.04 mm Hg (95 % CI -8.67 to +0.59, p=0.08) and -5.62 mm Hg (95 % CI -11.5 to +0.29, p=0.06) respectively after 6 weeks training. No diastolic blood pressure reductions were observed in either 5 % -0.97 mm Hg (95 % CI -2.56 to +0.62, p=0.20) or 10 % MVC +1.8 mm Hg (95 % CI -1.29 to +4.89, p=0.22) groups respectively after training. In those unable to complete isometric exercise at the traditional 30 % intensity, our results suggest there is no difference between 5 and 10 % groups and based on the principle of regression to the mean, this could mean both interventions induce a similar placebo-effect.
目前尚无关于等长运动训练的最低抗高血压阈值强度的研究。22名血压正常的参与者被随机分配到最大收缩力5%或10%的训练强度组。20名参与者完成了研究。在5%和10%的组中均观察到收缩压有临床意义但无统计学显著意义的降低——训练6周后，5%组收缩压降低4.04 mmHg（95%置信区间-8.67至+0.59，p=0.08），10%组收缩压降低5.62 mmHg（95%置信区间-11.5至+0.29，p=0.06）。训练后，5%组舒张压降低0.97 mmHg（95%置信区间-2.56至+0.62，p=0.20），10%最大随意收缩力组舒张压升高1.8 mmHg（95%置信区间-1.29至+4.89，p=0.22），两组均未观察到舒张压降低。对于那些无法以传统的30%强度完成等长运动的人，我们的结果表明5%和10%的组之间没有差异，基于均值回归原理，这可能意味着两种干预都产生了类似的安慰剂效应。
