Fleischer D, Cattau E, Sinofky E, Newsome J, Lack E, Andriuk A, Benjamin S
Department of Pathology, Georgetown University School of Medicine, Washington, D.C.
Endoscopy. 1989 Mar;21(2):81-5. doi: 10.1055/s-2007-1012906.
This work describes the initial results using a laser balloon in a canine model in an attempt to deliver the energy in a circumferential pattern. A balloon catheter, 2 cm long and 3 mm in diameter, was developed. Using a standard cw 100 watt Nd:YAG laser, a 600 micron fiber was tapered to 200 microns and passed through the proximal end of the balloon. Laparotomies were performed on mongrel dogs 14-18 kg in weight. After a gastrotomy, the gastric mucosa was exposed and rugal folds were pulled over the balloon to create a cylinder. Using power settings between 10 and 60 watts, and pulse durations between 10 and 40 seconds, radial energy was delivered and the tissue was examined for both gross and histologic effects. Circumferential zones of coagulation and necrosis were demonstrated.
这项工作描述了在犬类模型中使用激光球囊的初步结果，试图以圆周模式传递能量。开发了一种长2厘米、直径3毫米的球囊导管。使用标准的连续波100瓦钕:钇铝石榴石激光，将一根600微米的光纤逐渐变细至200微米，并穿过球囊的近端。对体重14 - 18千克的杂种犬进行剖腹手术。胃切开术后，暴露胃黏膜，将皱襞拉过球囊形成一个圆柱体。使用10至60瓦的功率设置和10至40秒的脉冲持续时间，传递径向能量，并检查组织的大体和组织学效应。显示出了凝血和坏死的圆周区域。
