Yan Caoxin, Bao Xiaofeng, Shentu Weihui, Chen Jian, Liu Chunmei, Ye Qin, Wang Liuhong, Tan Yangbin, Huang Pintong
Department of Ultrasound, The 2nd Affiliated Hospital of Zhejiang University College of Medicine, Hangzhou, China.
Department of Surgery, The 2nd Affiliated Hospital Zhejiang University College of Medicine, Hangzhou, China.
Ultrasound Med Biol. 2016 Jul;42(7):1431-40. doi: 10.1016/j.ultrasmedbio.2016.01.030. Epub 2016 Apr 9.
The aim of this study was to compare the accuracy of multi-detector computed tomography (MDCT) with double contrast-enhanced ultrasound (DCEUS), in which intravenous microbubbles are used alongside oral contrast-enhanced ultrasound, in determining the gross classification of patients with gastric carcinoma (GC). Altogether, 239 patients with GC proved by histology after endoscopic biopsy were included in this study. DCEUS and MDCT were performed pre-operatively. The diagnostic accuracies of DCEUS and MDCT in determining the gross classification were calculated and compared. The overall accuracy of DCEUS in determining the gross appearance of GC was higher than that of MDCT (84.9% vs. 79.9%, p < 0.001). There was no significant difference in accuracy between DCEUS and MDCT for Borrmann I and IV classifications of advanced gastric cancer (χ(2), p = 0.323 for Borrmann type I, p = 0.141 for Borrmann type IV). The accuracy of DCEUS for early GC and Borrmann II and III classifications of GC was higher than that of MDCT (χ(2), p = 0.000 for all). DCEUS may be regarded as a valuable complementary tool to MDCT in determining the gross appearance of gastric adenocarcinoma pre-operatively.
本研究旨在比较多排螺旋计算机断层扫描（MDCT）与双对比增强超声（DCEUS，即在口服对比增强超声的同时静脉注射微泡）在确定胃癌（GC）患者大体分类方面的准确性。本研究共纳入239例经内镜活检后组织学证实为GC的患者。术前进行了DCEUS和MDCT检查。计算并比较了DCEUS和MDCT在确定大体分类方面的诊断准确性。DCEUS在确定GC大体外观方面的总体准确性高于MDCT（84.9%对79.9%，p<0.001）。对于进展期胃癌的Borrmann I型和IV型分类，DCEUS和MDCT在准确性上无显著差异（χ²，Borrmann I型p = 0.323，Borrmann IV型p = 0.141）。DCEUS对早期GC以及GC的Borrmann II型和III型分类的准确性高于MDCT（χ²，所有p值均为0.000）。在术前确定胃腺癌的大体外观方面，DCEUS可被视为MDCT的一种有价值的补充工具。
