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心房调转术后大动脉完全转位女性的妊娠情况。来自波兰三个最大的成人先天性心脏病中心的一项研究。

Pregnancy in women with complete transposition of the great arteries following the atrial switch procedure. A study from three of the largest Adult Congenital Heart Disease centers in Poland.

作者信息

Lipczyńska Magdalena, Szymański Piotr, Trojnarska Olga, Tomkiewicz-Pająk Lidia, Pietrzak Bronisława, Klisiewicz Anna, Kumor Magdalena, Podolec Piotr, Hoffman Piotr

机构信息

a Department of Congenital Cardiac Defects , Institute of Cardiology , Warsaw , Poland.

b Department of Acquired Cardiac Defects , Institute of Cardiology , Warsaw , Poland.

出版信息

J Matern Fetal Neonatal Med. 2017 Mar;30(5):563-567. doi: 10.1080/14767058.2016.1177821. Epub 2016 May 5.

DOI:10.1080/14767058.2016.1177821
PMID:27072884
Abstract

OBJECTIVE

We sought to identify maternal/neonatal and cardiovascular complications in pregnant women with complete transposition of great arteries (D-TGA) following atrial switch.

METHODS

Clinical records of all women with D-TGA after the Mustard/Senning (M/S) operation who were followed at the three largest Adult Congenital Heart Disease (ACHD) centers in Poland were reviewed.

RESULTS

Fifteen of the fifty-nine women followed had a total of 24 pregnancies, including two spontaneous miscarriages. Twenty-two pregnancies (92%) resulted in a live birth, 91% were by cesarean section. During 5 (23%) of the 22 completed pregnancies obstetric complications were observed (one gestational diabetes, one hypertension in pregnancy, one placenta increta and two preterm labors). The mean pregnancy duration was 37.2 weeks (range: 26-41 weeks).We observed one neonatal death due to extreme prematurity. Six (25%) children had a birth weight of ≤2500 g. None of women had severe cardiac complications during pregnancy nor in the postpartum period.

CONCLUSIONS

In our study, we demonstrated a large number of obstetric complications and low birth weight in the presence of a systemic right ventricle. However, from a cardiologist's point of view pregnancy after the M/S operation was well-tolerated and relatively safe.

摘要

目的

我们试图确定大动脉完全转位(D-TGA)孕妇在心房调转术后的母婴及心血管并发症。

方法

回顾了波兰三家最大的成人先天性心脏病(ACHD)中心随访的所有接受Mustard/Senning(M/S)手术的D-TGA女性的临床记录。

结果

59名接受随访的女性中有15名共怀孕24次,其中包括2次自然流产。22次怀孕(92%)分娩活婴,91%通过剖宫产。在22次足月妊娠中有5次(23%)观察到产科并发症(1例妊娠期糖尿病、1例妊娠期高血压、1例胎盘植入和2例早产)。平均妊娠时长为37.2周(范围:26 - 41周)。我们观察到1例因极度早产导致的新生儿死亡。6名(25%)儿童出生体重≤2500g。所有女性在孕期及产后均未出现严重心脏并发症。

结论

在我们的研究中,我们证实在存在体循环右心室的情况下会出现大量产科并发症及低出生体重。然而,从心脏病专家的角度来看,M/S手术后的妊娠耐受性良好且相对安全。

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