Liang Chen, Liang Qianlei, DU Changwang, Zhang Xiaodong, Guo Shiwen
Department of Neurosurgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China.
Department of Neurosurgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130033, P.R. China.
Oncol Lett. 2016 Apr;11(4):2625-2628. doi: 10.3892/ol.2016.4256. Epub 2016 Feb 22.
Langerhans' cell histiocytosis (LCH) is a rare disease with a wide spectrum of clinical manifestations, varying from an isolated lesion to systemic involvement. The etiology of this disease remains to be elucidated. The present study reports a case of LCH with temporal fossa localization in an 8-year-old male patient, who had exhibited left temporal pain and headache for 1 month. Physical examination revealed slight exophthalmos and conjunctival hemorrhage in the patient's left eye, and non-contrast computed tomography imaging of the head revealed a soft tissue mass with unclear margins located in the left temporal fossa, as well as a wide bony defect. Magnetic resonance imaging revealed a heterogeneously contrast-enhanced mass near the left temporal pole, which eroded into the patient's left orbit and maxillary sinus. The lesion was totally excised and confirmed to be LCH through biopsy.
朗格汉斯细胞组织细胞增多症（LCH）是一种罕见疾病，临床表现范围广泛，从孤立性病变到全身受累不等。该疾病的病因仍有待阐明。本研究报告了一例8岁男性患者颞窝定位的LCH病例，该患者出现左侧颞部疼痛和头痛1个月。体格检查发现患者左眼轻度眼球突出和结膜出血，头部非增强计算机断层扫描成像显示左侧颞窝有一个边界不清的软组织肿块，以及一个广泛的骨质缺损。磁共振成像显示左侧颞极附近有一个不均匀强化的肿块，该肿块侵蚀到患者的左侧眼眶和上颌窦。病变被完全切除，并通过活检确诊为LCH。
