Alrowaili Ziyad A, Lerch Michael L F, Petasecca Marco, Carolan Martin G, Metcalfe Peter E, Rosenfeld Anatoly B
University of Wollongong; Aljouf University.
J Appl Clin Med Phys. 2016 Mar 8;17(2):85-98. doi: 10.1120/jacmp.v17i2.5932.
The main objective of this study is to demonstrate the performance characteristics of the Magic Plate (MP) system when operated upstream of the patient in trans-mission mode (MPTM). The MPTM is an essential component of a real-time QA system designed for operation during radiotherapy treatment. Of particular interest is a quantitative study into the influence of the MP on the radiation beam quality at several field sizes and linear accelerator potential differences. The impact is measured through beam perturbation effects such as changes in the skin dose and/or percentage depth dose (PDD) (both in and out of field). The MP was placed in the block tray of a Varian linac head operated at 6, 10 and 18 MV beam energy. To optimize the MPTM operational setup, two conditions were investigated and each setup was compared to the case where no MP is positioned in place (i.e., open field): (i) MPTM alone and (ii) MPTM with a thin passive contamination electron filter. The in-field and out-of-field surface doses of a solid water phantom were investigated for both setups using a Markus plane parallel (Model N23343) and Attix parallel-plate, MRI model 449 ionization chambers. In addition, the effect on the 2D dose distribution measured by the Delta4 QA system was also investi-gated. The transmission factor for both of these MPTM setups in the central axis was also investigated using a Farmer ionization chamber (Model 2571A) and an Attix ionization chamber. Measurements were performed for different irradiation field sizes of 5 × 5 cm2 and 10 × 10 cm2. The change in the surface dose relative to dmax was measured to be less than 0.5% for the 6 MV, 10 MV, and 18 MV energy beams. Transmission factors measured for both set ups (i & ii above) with 6 MV, 10 MV, and 18 MV at a depth of dmax and a depth of 10 cm were all within 1.6% of open field. The impact of both the bare MPTM and the MPTM with 1 mm buildup on 3D dose distribution in comparison to the open field investigated using the Delta4 system and both the MPTM versions passed standard clinical gamma analysis criteria. Two MPTM operational setups were studied and presented in this article. The results indicate that both versions may be suitable for the new real-time megavoltage photon treatment delivery QA system under development. However, the bare MPTM appears to be slightly better suited of the two MP versions, as it minimally perturbs the radiation field and does not lead to any significant increase in skin dose to the patient.
本研究的主要目的是展示魔板(MP)系统在透射模式下于患者上游运行时(MPTM)的性能特征。MPTM是为放射治疗期间运行而设计的实时质量保证(QA)系统的重要组成部分。特别值得关注的是对MP在几种射野尺寸和直线加速器电位差下对辐射束质量影响的定量研究。通过诸如皮肤剂量和/或百分深度剂量(PDD)(射野内和射野外)变化等束流扰动效应来测量其影响。MP放置在瓦里安直线加速器机头的挡块托盘内,以6、10和18MV的束流能量运行。为了优化MPTM的操作设置,研究了两种情况,并将每种设置与未放置MP的情况(即开放射野)进行比较:(i)单独的MPTM和(ii)带有薄的无源污染电子滤波器的MPTM。使用马克斯平面平行电离室(型号N23343)和阿蒂克斯平行板MRI型号449电离室,对两种设置下固体水模体的射野内和射野外表面剂量进行了研究。此外,还研究了对Delta4 QA系统测量的二维剂量分布的影响。还使用 Farmer电离室(型号2571A)和阿蒂克斯电离室研究了这两种MPTM设置在中心轴上的透射因子。对5×5 cm2和10×10 cm2的不同照射野尺寸进行了测量。对于6MV、10MV和18MV能量束,相对于dmax的表面剂量变化测量值小于0.5%。在dmax深度和10 cm深度处,用6MV、10MV和18MV对上述两种设置(i和ii)测量的透射因子均在开放射野的1.6%以内。使用Delta4系统研究了裸MPTM和带有1mm建成层的MPTM对三维剂量分布的影响,两种MPTM版本均通过了标准临床伽马分析标准。本文研究并介绍了两种MPTM操作设置。结果表明,这两种版本可能都适用于正在开发的新型实时兆伏级光子治疗输送QA系统。然而,在这两种MP版本中,裸MPTM似乎更适合一些,因为它对辐射野的扰动最小,并且不会导致患者皮肤剂量有任何显著增加。