Mallat M, Houlgatte R, Brachet P, Prochiantz A
INSERUM U114, Collège de France, Paris.
Dev Biol. 1989 May;133(1):309-11. doi: 10.1016/0012-1606(89)90322-9.
Amoeboid microglial cells purified from primary cultures of embryonic rat brains and stimulated with bacterial lipopolysaccharides released high amounts of nerve growth factor. This finding suggests that brain macrophages play a major neurotrophic role during development, in adulthood, and in the regenerative events that follow localized lesions.
从胚胎大鼠脑原代培养物中纯化出的阿米巴样小胶质细胞,在用细菌脂多糖刺激后会释放大量神经生长因子。这一发现表明,脑巨噬细胞在发育过程、成年期以及局部损伤后的再生过程中发挥着主要的神经营养作用。