Selypes A, László A, Virág I
Department of Hygiene and Epidemiology, University Medical School, Szeged, Hungary.
Haematologia (Budap). 1989;22(1):19-24.
A six-hour culture of unstimulated peripheral blood from a patient with childhood erythroleukaemia was examined for chromosome karyotype. The characteristic chromosomal abnormalities of erythroleukaemia del (5q) and monosomy 7 were found in this case together with a marker chromosome and other chromosomal abnormalities. The results suggest the usefulness of this simple method in the cytogenetic diagnosis of some types of leukaemias.
对一名儿童红白血病患者未受刺激的外周血进行了6小时培养,以检查染色体核型。在该病例中发现了红白血病特征性的染色体异常——5号染色体长臂缺失(del(5q))和7号染色体单体,同时还发现了一条标记染色体及其他染色体异常。结果表明这种简单方法在某些类型白血病的细胞遗传学诊断中具有实用性。