Wahaj Aiyesha, Hafeez Kashif, Zafar Muhammad Sohail
a Department of Orthodontics , Dr. Ishrat-ul-Ebad Khan Institute of Oral Health Sciences, Dow University , Karachi , Pakistan.
b Oxford Deanery, Broadshires Dental Practice , Carterton , Oxon, OX18 1JA , UK.
Cranio. 2017 Jan;35(1):4-9. doi: 10.1080/08869634.2016.1156282. Epub 2016 Apr 8.
This study reviewed the dental literature in order to determine the association of bone marrow edema with osteoarthritis and temporomandibular joint (TMJ) internal derangement disorders.
A literature search was performed using electronic databases PubMed/Medline (National Library of Medicine, Bethesda, Maryland) and Cochrane for articles published during the last 15 years (January 2000-December 2014). A predetermined inclusion and exclusion criteria were used for filtering the scientific papers. Research articles fulfilling the basic inclusion criteria were included in the review.
The reviewed studies showed that bone marrow edema is found in painful joints with osteoarthritis in a majority of cases. A few cases with no pain or significant degenerative changes are reported to have a bone marrow edema pattern as well.
Bone marrow edema, increased fluid level, and pain are associated with osteoarthritis in the majority of patients reporting TMJ arthritis. Degenerative and disc displacement conditions are multifactorial and require further investigations. Magnetic resonance imaging can be employed to detect bone marrow edema even in the absence of pain and clinical symptoms in the patients of internal derangements.
本研究回顾牙科文献，以确定骨髓水肿与骨关节炎及颞下颌关节（TMJ）内紊乱疾病之间的关联。
利用电子数据库PubMed/Medline（美国国立医学图书馆，马里兰州贝塞斯达）和Cochrane检索过去15年（2000年1月至2014年12月）发表的文章。使用预先确定的纳入和排除标准筛选科学论文。符合基本纳入标准的研究文章被纳入综述。
综述研究表明，大多数情况下，在患有骨关节炎的疼痛关节中可发现骨髓水肿。也有少数无痛或无明显退行性改变的病例报告存在骨髓水肿模式。
在大多数报告颞下颌关节关节炎的患者中，骨髓水肿、液平面升高和疼痛与骨关节炎相关。退行性变和盘移位情况是多因素的，需要进一步研究。即使在颞下颌关节内紊乱患者无疼痛和临床症状时，磁共振成像也可用于检测骨髓水肿。
