Kobyliansky E, Livshits G, Otremski I
Hum Biol. 1989 Feb;61(1):13-29.
The primary purpose of the present study was to examine the comparative incidence of some common diseases with unknown genetic components (e.g. newborn jaundice, urinary and respiratory tract infections) in infants of Israeli families of mixed and non-mixed ethnic origin. We also studied possible relationships between risk of these diseases and a number of anthropometric and demographic factors. Only the group of infants whose parents originated from North Africa and Middle East showed statistically significant differences: namely an increased level of total morbidity, of various comparisons of specific disease frequencies, and in total illness frequency, between infants from "mixed" and "non-mixed" families. In general, however, there was a positive correlation between frequency of healthy infants in "mixed" group and genetic distance between parents. Our findings also indicated a significant association between weight and head circumference of newborn infants respectively, and their illnesses, especially jaundice.
本研究的主要目的是调查以色列不同种族和非不同种族家庭的婴儿中一些具有未知遗传成分的常见疾病(如新生儿黄疸、泌尿道和呼吸道感染)的相对发病率。我们还研究了这些疾病的风险与一些人体测量和人口统计学因素之间的可能关系。只有父母来自北非和中东的婴儿组显示出统计学上的显著差异:即在“混合”和“非混合”家庭的婴儿之间,总发病率、特定疾病频率的各种比较以及总疾病频率都有所增加。然而,总体而言,“混合”组中健康婴儿的频率与父母之间的遗传距离呈正相关。我们的研究结果还表明,新生儿的体重和头围分别与他们的疾病,尤其是黄疸之间存在显著关联。