Meneses M F, Ostrowski M L
Department of Anatomic Pathology, University Hospital, Jacksonville, FL 32209.
Hum Pathol. 1989 May;20(5):486-8. doi: 10.1016/0046-8177(89)90015-4.
Splenic-gonadal fusion is an extremely rare congenital anomaly that results from fusion between the splenic and gonadal anlage during embryonic development. Approximately 90 cases have been reported in the literature. The condition has been divided into two major subgroups: continuous splenic-gonadal fusion in which a continuous cord-like structure connects the spleen and the gonadal-mesonephric structures, and discontinuous splenic-gonadal fusion in which no such connection exists. We report a case of discontinuous splenic-gonadal fusion in an adult women with no evidence of other anomalies or malformations, the fifth reported case of splenic-gonadal fusion occurring in a female. To our knowledge, this is the first case of discontinuous splenic-gonadal fusion reported in a female patient, and the second case of splenic-gonadal fusion reported in an adult woman.
脾-性腺融合是一种极其罕见的先天性异常，它是在胚胎发育过程中脾和性腺原基之间融合所致。文献中已报道了约90例病例。这种情况已被分为两个主要亚组：连续性脾-性腺融合，即一条连续的索状结构连接脾脏和性腺-中肾结构；以及非连续性脾-性腺融合，即不存在这种连接。我们报告了一例成年女性非连续性脾-性腺融合病例，该女性无其他异常或畸形证据，这是第五例报道的女性脾-性腺融合病例。据我们所知，这是女性患者中报道的首例非连续性脾-性腺融合病例，也是成年女性中报道的第二例脾-性腺融合病例。
