Ernst Diana, Witte Torsten
Dtsch Med Wochenschr. 2016 Apr;141(8):544-50. doi: 10.1055/s-0041-111436. Epub 2016 Apr 14.
Sjögren's syndrome is a frequent autoimmune disease and is associated with a lymphocytic infiltration of the lachrymal and salivary glands and with sicca symptoms. Its diagnostic procedures consist of the quantification of tear and saliva production, identification of extraglandular manifestations, measurement of antibodies against SS-A and SS-B and of salivary gland biopsies. Dry eyes and dry mouth are treated only symptomatically, whereas extraglandular manifestations are treated similar to systemic lupus erythematosus.
干燥综合征是一种常见的自身免疫性疾病,与泪腺和唾液腺的淋巴细胞浸润以及干燥症状相关。其诊断程序包括泪液和唾液分泌量的量化、腺体外表现的识别、抗SS-A和SS-B抗体的检测以及唾液腺活检。干眼症和口干仅进行对症治疗,而腺体外表现的治疗与系统性红斑狼疮相似。