新生血管性年龄相关性黄斑变性各亚型的眼底自发荧光缺损模式
PATTERNS OF FUNDUS AUTOFLUORESCENCE DEFECTS IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION SUBTYPES.
作者信息
Ozkok Ahmet, Sigford Douglas K, Tezel Tongalp H
机构信息
*Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, Kentucky; and †Department of Ophthalmology, Columbia University, New York, New York.
出版信息
Retina. 2016 Nov;36(11):2191-2196. doi: 10.1097/IAE.0000000000001034.
PURPOSE
To test define characteristic fundus autofluorescence patterns of different exudative age-related macular degeneration subtypes.
METHODS
Cross-sectional study. Fifty-two patients with choroidal neovascularization because of three different neovascular age-related macular degeneration subtypes were included in the study. Macular and peripheral fundus autofluorescence patterns of study subjects were compared in a masked fashion.
RESULTS
Fundus autofluorescence patterns of all three neovascular age-related macular degeneration subtypes revealed similar patterns. However, peripapillary hypo-autofluorescence was more common among patients with polypoidal choroidal vasculopathy (88.2%) compared with patients with retinal angiomatous proliferation (12.5%) and patients without retinal angiomatous proliferation and polypoidal choroidal vasculopathy (21.1%) (P < 0.0001).
CONCLUSION
Presence of peripapillary fundus autofluorescence defects in neovascular age-related macular degeneration maybe suggestive of polypoidal choroidal vasculopathy as a variant of neovascular age-related macular degeneration.
目的
确定不同渗出性年龄相关性黄斑变性亚型的特征性眼底自发荧光模式。
方法
横断面研究。纳入52例因三种不同的新生血管性年龄相关性黄斑变性亚型而出现脉络膜新生血管的患者。以盲法比较研究对象的黄斑和周边眼底自发荧光模式。
结果
所有三种新生血管性年龄相关性黄斑变性亚型的眼底自发荧光模式显示出相似的模式。然而，与视网膜血管瘤样增生患者（12.5%）和无视网膜血管瘤样增生及息肉状脉络膜血管病变患者（21.1%）相比，息肉状脉络膜血管病变患者中视乳头周围低自发荧光更为常见（88.2%）（P<0.0001）。
结论
新生血管性年龄相关性黄斑变性中视乳头周围眼底自发荧光缺陷的存在可能提示息肉状脉络膜血管病变是新生血管性年龄相关性黄斑变性的一种变体。
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