He Yinbo, Zhang Longbin, Xiao Jianghong, Duan Baofeng
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2015 Dec;32(6):1288-93.
Intensity-modulated radiotherapy planning for nasopharyngeal carcinoma is very complex. The quality of plan is often closely linked to the experience of the treatment planner. In this study, 10 nasopharyngeal carcinoma patients at different stages were enrolled. Based on the scripting of Pinnacle 9. 2 treatment planning system, the computer program was used to set the basic parameters and objective parameters of the plans. At last, the nasopharyngeal carcinoma intensity-modulated radiotherapy plans were completed automatically. Then, the automatical and manual intensity-modulated radiotherapy plans were statistically compared and clinically evaluated. The results showed that there were no significant differences between those two kinds of plans with respect to the dosimetry parameters of most targets and organs at risk. The automatical nasopharyngeal carcinoma intensity-modulated radiotherapy plans can meet the requirements of clinical radiotherapy, significantly reduce planning time, and avoid the influence of human factors such as lack of experience to the quality of plan.
鼻咽癌的调强放射治疗计划非常复杂。计划的质量往往与治疗计划者的经验密切相关。本研究纳入了10例不同分期的鼻咽癌患者。基于Pinnacle 9. 2治疗计划系统的脚本，使用计算机程序设置计划的基本参数和目标参数。最后，自动完成鼻咽癌调强放射治疗计划。然后，对自动和手动调强放射治疗计划进行统计学比较和临床评估。结果表明，两种计划在大多数靶区和危及器官的剂量学参数方面无显著差异。自动鼻咽癌调强放射治疗计划能够满足临床放射治疗的要求，显著缩短计划时间，避免经验不足等人为因素对计划质量的影响。
